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Selective TYK2 inhibitor safe, works against psoriatic arthritis
Deucravacitinib, a selective TYK2 inhibitor, is well tolerated and appears to produce marked improvements in American College of Rheumatology 20 (ACR20) and other endpoints in the treatment of patients with psoriatic arthritis (PsA), according to the results of a phase II study.
Selective TYK2 inhibitor safe, works against psoriatic arthritis
08 Mar 2022Schizophrenia genetics not linked to neuropsychiatric features in childhood-onset SLE
No apparent association exists between neuropsychiatric systemic lupus erythematosus (NPSLE) and known risk loci for schizophrenia in a multiethnic cohort of patients with childhood-onset (c)SLE, reveals a recent study.
Schizophrenia genetics not linked to neuropsychiatric features in childhood-onset SLE
28 Feb 2022Sarcoidosis patients at risk of haematologic, nonmelanoma skin cancers
Sarcoidosis patients with biopsy-verified non-necrotizing granulomatous inflammation are at greater risk of haematologic cancers and nonmelanoma skin cancer (NMSC) in the long term than the general population, a study has found.
Sarcoidosis patients at risk of haematologic, nonmelanoma skin cancers
25 Feb 2022Baricitinib keeps radiographic progression levels low in rheumatoid arthritis
Treatment with oral baricitinib steadily inhibits radiographic progression of structural joint damage in most patients with rheumatoid arthritis (RA), while achieving clinical improvement in disease activity, through 5 years as compared with initial conventional synthetic disease-modifying antirheumatic drug (csDMARD) or placebo, results of a study have shown.
Baricitinib keeps radiographic progression levels low in rheumatoid arthritis
24 Feb 2022Are patients with psoriatic arthritis at higher risk of death?
Patients with psoriatic arthritis (PsA) do not appear to be at increased risk of mortality from all causes, reveals a study. Moreover, the specific proportionate mortality rate (PMR) in this cohort is similar to that of the general population.
Are patients with psoriatic arthritis at higher risk of death?
23 Feb 2022First-line biologic therapy persists longer than later agents in ankylosing spondylitis
Biologic disease-modifying antirheumatic drug (bDMARD) therapy is effective in reducing ankylosing spondylitis (AS) disease activity, reports a study, noting how treatment has persisted for up to 8 years among patients remaining on their first bDMARD, which is longer than on subsequent agents.
First-line biologic therapy persists longer than later agents in ankylosing spondylitis
22 Feb 2022Lower SLERPI cutoff improves early diagnosis in SLE patients with fever, thrombosis
Hospitalization is warranted in one in five patients with new-onset systemic lupus erythematosus (SLE) manifest disease presentations, according to a recent study. Of note, diagnosis has been delayed in nearly 20 percent of patients.