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Add-on bevacizumab ups hypertension risk in CRC patients
The addition of bevacizumab (BVZ) to the standard regimen for the treatment of advanced colorectal cancer (CRC) appears to increase the risk of cardiovascular events, suggest the results of a meta-analysis presented at the recent ASCO Gastrointestinal Cancers Symposium (ASCO GI 2023).
Add-on bevacizumab ups hypertension risk in CRC patients
03 Feb 2023Is hypofractionated better than conventionally fractionated RT for stage I NSCLC?
Hypofractionated radiotherapy (HFRT) is not superior to conventionally fractionated radiotherapy (CFRT) in providing survival benefits to patients with stage I nonsmall cell lung cancer (NSCLC), but HFRT is preferable due to its convenience and lower costs, according to a study.
Is hypofractionated better than conventionally fractionated RT for stage I NSCLC?
03 Feb 2023Tislelizumab–chemotherapy combo poised as new first-line option for advanced gastric cancer
Adding the anti-PD-1 monoclonal antibody tislelizumab to chemotherapy in the first-line treatment of PD-1-positive advanced gastric or gastroesophageal junction adenocarcinoma appears to produce significant and clinically meaningful improvements in survival outcomes while having an acceptable safety profile, according to interim data from the phase III RATIONALE 305 trial.
Tislelizumab–chemotherapy combo poised as new first-line option for advanced gastric cancer
03 Feb 2023Saroglitazar may lower cardiovascular risk in NAFLD
Treatment with the dual PPAR α/γ agonist saroglitazar helps improve the serum atherogenic lipoprotein profile in patients with nonalcoholic fatty liver disease (NAFLD), regardless of comorbid conditions and statin use, as shown in a study.
Saroglitazar may lower cardiovascular risk in NAFLD
03 Feb 2023EULAST: No clear benefits in prescribing long-acting over oral antipsychotics for early-phase schizophrenia
Long-acting injectable antipsychotics (LAIAs) showed no substantial advantage over oral antipsychotics in terms of time to discontinuation in patients with early-phase schizophrenia, the EULAST trial has demonstrated.
EULAST: No clear benefits in prescribing long-acting over oral antipsychotics for early-phase schizophrenia
03 Feb 2023Palliative RT relieves pain in end-stage liver cancer
Treatment with single fraction radiation therapy (RT) results in lesser hepatic pain in most patients with end-stage hepatocellular carcinoma (HCC) or liver metastases, according to a study presented at the recent ASCO Gastrointestinal Cancers Symposium (ASCO GI 2023).