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Sofosbuvir/velpatasvir effective, safe for paediatric HCV
The direct-acting antiviral (DAA) sofosbuvir/velpatasvir (SOF/VEL) was effective and safe for the treatment of chronic hepatitis C virus (HCV) infection in individuals aged 6–18 years, the PANDAA-PED study has shown.
Sofosbuvir/velpatasvir effective, safe for paediatric HCV
25 May 20232-dose, 3-dose vax schedules active against several meningococcal serogroup B strains
Both the 2-dose and 3-dose vaccination schedules of the four-component meningococcal serogroup B vaccine (4CMenB) appear to provide protection against a panel epidemiologically relevant strains in adolescents and young adults, according to a phase III study presented at ESPID 2023.
2-dose, 3-dose vax schedules active against several meningococcal serogroup B strains
25 May 2023SGLT2 inhibitors reduce HCC risk in T2DM patients with CHB
The use of sodium-glucose cotransporter 2 (SGLT2) inhibitors is associated with a reduced risk of incident hepatocellular carcinoma (HCC) in patients with coexisting type 2 diabetes mellitus (T2DM) and chronic hepatitis B (CHB), a territory-wide cohort study in Hong Kong has shown.
SGLT2 inhibitors reduce HCC risk in T2DM patients with CHB
18 May 2023Dengue vaccine provides ample protection to children
The dengue vaccine confers substantial protective benefit on children aged 10 to 15 years, reports a study in the Philippines, which was presented at the recent ESPID 2023.
Dengue vaccine provides ample protection to children
17 May 2023Algorithm useful in evaluating COVID-19 reinfection cases in Singapore
A study from Singapore demonstrated the usefulness of a systematic programme using combined microbiologic, serologic, and genomic criteria to assess possible COVID-19 reinfection cases.
Algorithm useful in evaluating COVID-19 reinfection cases in Singapore
16 May 2023Weight gain persists, obesity rises in children after pandemic lockdown
Some children, particularly boys, continue to gain weight even after COVID-19 pandemic lockdown measures have been eased, indicating the challenges in reversing the effects of lockdowns, reveals a study in Argentina. However, sedentary behaviours have decreased while quality of life has improved.
Weight gain persists, obesity rises in children after pandemic lockdown
12 May 2023Influenza vaccine wards off cardiovascular events, death in CAD patients
A meta-analysis of randomized trials has revealed that influenza vaccination is effective at preventing all-cause mortality, cardiovascular mortality, major acute cardiovascular events, and acute coronary syndrome (ACS) among patients with coronary artery disease (CAD), particularly in those with ACS.