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Two phase III trials reflect the sustained efficacy and safety of the bDMARD* ixekizumab in bDMARD-naïve (COAST-V) or TNFi**-experienced (COAST-W) adults with active radiographic axial spondyloarthritis (r-axSpA), also known as ankylosing spondylitis (AS).
The novel rifabutin-based triple therapy (RHB-105) delivers promising outcomes as first-line empirical treatment for Helicobacter pylori eradication, according to the results of a phase III, double blind trial. This therapy addresses the challenge of rising antibiotic resistance in the current environment.
Patients with axial and peripheral psoriatic arthritis (PsA) who switch to a second or third tumour necrosis factor inhibitor (TNFi) have significantly lower drug survival and response rates, a recent study has found.
The immune checkpoint inhibitor nivolumab yields long-term overall survival (OS) gains in treatment-experienced patients with gastric/gastroesophageal junction (G/GEJ), with the benefit most pronounced among those who show a complete (CR) or partial response (PR), according to the 2-year follow-up results of the phase III ATTRACTION-2a study.
Singapore’s Ministry of Health (MOH) has confirmed 876 new cases of COVID-19 infection on May 10. Two casualties have been recorded on May 6, bringing the total COVID-19 deaths in the city-state to 20. Older age seems a common factor among them.
After months of work disruption, profound worrying, social distancing, and isolation, SARS-CoV-2* still rages on, unyielding to human interventions.
Adults who develop peanut allergy in adulthood are less likely to receive a physician diagnosis of their allergy or use epinephrine compared with those with childhood-onset peanut allergy, according to a study from the US.
Use of the interleukin(IL)-1 inhibitor anakinra led to clinical improvements in patients with coronavirus disease (COVID)-19, acute respiratory distress syndrome (ARDS), and systemic inflammation who are under noninvasive ventilation outside the intensive care unit (ICU), an Italian retrospective study has shown.
Treatment with trametinib, an MEK inhibitor, significantly improves progression-free survival (PFS) in patients with recurrent low-grade serous ovarian or peritoneal carcinoma (LGSOC) compared with standard of care (SOC), according to a study presented at SGO 20/20.
Adding trastuzumab to a chemotherapy backbone of carboplatin and paclitaxel led to sustained survival benefit in patients with recurrent/advanced, HER2-positive uterine serous carcinoma compared with chemotherapy alone, according to an updated survival analysis presented at SGO 2020 Meeting.
