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Upfront ASCT + RVd improves PFS in NDMM
Upfront autologous stem cell transplantation (ASCT) plus lenalidomide, bortezomib, and dexamethasone (RVd) significantly improves progression-free survival (PFS) in patients with newly diagnosed multiple myeloma (NDMM), results of the phase III DETERMINATION trial showed.
Upfront ASCT + RVd improves PFS in NDMM
16 Jul 2022Family history plus obesity/hyperglycaemia redoubles renal cell cancer risk
The interaction between genetic and environmental factors, specifically obesity and hyperglycaemia, contributes to an increased risk of renal cell cancer (RCC), suggests a study.
Family history plus obesity/hyperglycaemia redoubles renal cell cancer risk
16 Jul 2022HCV ups kidney disease risk even after resolution
Both resolved and chronic infections of hepatitis C virus (HCV) lead to a higher risk of developing kidney disease, a recent study has found. This effect is further pronounced in genotype 1 HCV.
HCV ups kidney disease risk even after resolution
16 Jul 2022Meta-analysis favours citalopram in poststroke recovery
Selective serotonin reuptake inhibitors (SSRIs) can prevent and treat depression following stroke, in addition to improving anxiety, dependence, motor function, and cognitive function—benefits that are only reproducible with citalopram but not fluoxetine, according to a meta-analysis said to be the most up to date.
Meta-analysis favours citalopram in poststroke recovery
15 Jul 2022Nonoperative management safe, feasible after complete response in rectal cancer
Patients with locally advanced rectal cancer who achieve complete response (CR) following sequential short-course radiation therapy (SCRT) and chemotherapy appear to benefit from nonoperative management (NOM) with a watch-and-wait strategy, which presents evidence for good anorectal functions, results of a study have shown.