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Disrupted gut fungi tied to colorectal cancer
Alterations in normal gut mycobiota profile, particularly the enrichment of the pathogenic Aspergillus rambellii, appear to aggravate the risk of colorectal cancer (CRC), according to a recent study.
Disrupted gut fungi tied to colorectal cancer
14 Jul 2022
Panitumumab + mFOLFOX6 ups OS in 1L left-sided RAS wild-type mCRC in Japanese trial
Panitumumab plus modified FOLFOX6 (mFOLFOX6; fluorouracil, leucovorin, and oxaliplatin) as first-line therapy significantly improves overall survival (OS) vs bevacizumab plus mFOLFOX6 in patients with left-sided RAS wild-type (wt) metastatic colorectal cancer (mCRC), results of the Japanese PARADIGM trial have shown.
Panitumumab + mFOLFOX6 ups OS in 1L left-sided RAS wild-type mCRC in Japanese trial
14 Jul 2022
Upadacitinib works in select ankylosing spondylitis patients
The Janus kinase inhibitor upadacitinib induces significantly higher response than placebo in ankylosing spondylitis patients with inadequate response to biological disease-modifying antirheumatic drugs, without introducing new safety signals, according to data from a phase III trial.
Upadacitinib works in select ankylosing spondylitis patients
14 Jul 2022
Skipping breakfast protects against age-related macular degeneration
Older people who intermittently fast by skipping breakfast appear to have a reduced risk of age-related macular degeneration, a study has found.
Skipping breakfast protects against age-related macular degeneration
14 Jul 2022
Venetoclax-obinutuzumab ± ibrutinib induces PFS benefit in CLL
A time-limited regimen of venetoclax plus obinutuzumab with or without ibrutinib improved progression-free survival (PFS) in fit, treatment-naïve patients with chronic lymphocytic leukaemia (CLL), according to results of the phase III GAIA/CLL13 trial presented at EHA 2022.
Venetoclax-obinutuzumab ± ibrutinib induces PFS benefit in CLL
13 Jul 2022
Low vitamin D tied to lower risk of radiologic osteoarthritis in older men
A recent Korea study has found that low levels of vitamin D appear to be significantly protective against radiologic osteoarthritis (ROA) in older men but not women.
