News & Updates

Preservative-free albuterol formulations safer for children with asthma

13 Apr 2020 by

In the management of children hospitalized with severe asthma exacerbations, preservative-free albuterol formulations are safer for use in continuous nebulization compared with a benzalkonium chloride (BAC)-containing formulation, which is associated with longer treatment duration and additional respiratory support, as shown in a recent study.

Preservative-free albuterol formulations safer for children with asthma

13 Apr 2020

Delayed denosumab injections tied to reduced BMD response

13 Apr 2020

Delays in injections of denosumab lead to suboptimal bone mineral density (BMD) response at both spine and total hip, results of a recent study have shown.

Delayed denosumab injections tied to reduced BMD response

13 Apr 2020

HPV infection bears increased risk of psoriasis

13 Apr 2020

Individuals with human papillomavirus (HPV) infection are at higher risk of psoriasis, with the risk increasing in accordance with age, a study has found.

HPV infection bears increased risk of psoriasis

13 Apr 2020

Bone mass higher in HIV+ children on efavirenz than lopinavir/ritonavir

13 Apr 2020 by

Children with HIV (HIV+) who switched to efavirenz had higher bone mass even after 4 years of switching compared with those who remained on an antiretroviral therapy (ART) regimen comprising lopinavir and ritonavir, according to data presented at CROI 2020.

Bone mass higher in HIV+ children on efavirenz than lopinavir/ritonavir

13 Apr 2020

APT-1011 shows clinical activity in teens, adults with eosinophilic esophagitis

12 Apr 2020

The orally disintegrating tablet formulation of fluticasone propionate, APT‐1011, is safe and well tolerated in adolescents and adults with eosinophilic esophagitis (EoE), according to the results of a phase Ib/IIa trial. Treatment produces improvements in both endoscopic and histologic findings, as well as symptoms.

APT-1011 shows clinical activity in teens, adults with eosinophilic esophagitis

12 Apr 2020

Minesapride beneficial to patients with irritable bowel syndrome

11 Apr 2020

Treatment with minesapride in patients with irritable bowel syndrome with constipation (IBS-C) is well tolerated and helps improve stool frequency, as well as abdominal and overall symptoms, according to the results of a phase II study from Japan.

Minesapride beneficial to patients with irritable bowel syndrome

11 Apr 2020

Dasatinib improves outcomes in paediatric ALL

11 Apr 2020 by

Dasatinib outperforms imatinib in the treatment of Philadelphia chromosome–positive acute lymphoblastic leukaemia (ALL) in children, providing superior control of central nervous system (CNS) leukaemia without increasing toxicity and while doing away with prophylactic cranial irradiation, according to the results of the phase III CCCGALL-2015* trial.

Dasatinib improves outcomes in paediatric ALL

11 Apr 2020

Ambrisentan–tadalafil combo effective against connective tissue disease-related PAH

10 Apr 2020

Combination therapy with ambrisentan plus tadalafil provides greater benefits than either agent alone in patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH), especially those with typical PAH haemodynamic characteristics at baseline, according to a posthoc analysis of the AMBITION* study.

Ambrisentan–tadalafil combo effective against connective tissue disease-related PAH

10 Apr 2020

Proton pump inhibitor use poses increased stone risk

09 Apr 2020

Use of proton pump inhibitors appears to contribute to a higher risk of developing kidney stones in a dose-dependent fashion, as shown in a study. Likewise, histamine-2 receptor antagonists are associated with a risk increase, suggesting the possibility of acid suppression as an underlying mechanism.

Proton pump inhibitor use poses increased stone risk

09 Apr 2020

Teprotumumab casts hope for thyroid eye disease

09 Apr 2020 by

The human monoclonal anti-IGF-1R* antibody teprotumumab was effective in reducing proptosis or eye bulging in patients with the rare thyroid eye disease (TED) regardless of age, gender, and/or smoking status, according to pooled data presented at ENDO 2020.

Teprotumumab casts hope for thyroid eye disease

09 Apr 2020

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Preservative-free albuterol formulations safer for children with asthma

Preservative-free albuterol formulations safer for children with asthma

Delayed denosumab injections tied to reduced BMD response

Delayed denosumab injections tied to reduced BMD response

HPV infection bears increased risk of psoriasis

HPV infection bears increased risk of psoriasis

Bone mass higher in HIV+ children on efavirenz than lopinavir/ritonavir

Bone mass higher in HIV+ children on efavirenz than lopinavir/ritonavir

APT-1011 shows clinical activity in teens, adults with eosinophilic esophagitis

APT-1011 shows clinical activity in teens, adults with eosinophilic esophagitis

Minesapride beneficial to patients with irritable bowel syndrome

Minesapride beneficial to patients with irritable bowel syndrome

Dasatinib improves outcomes in paediatric ALL

Dasatinib improves outcomes in paediatric ALL

Ambrisentan–tadalafil combo effective against connective tissue disease-related PAH

Ambrisentan–tadalafil combo effective against connective tissue disease-related PAH

Proton pump inhibitor use poses increased stone risk

Proton pump inhibitor use poses increased stone risk

Teprotumumab casts hope for thyroid eye disease

Teprotumumab casts hope for thyroid eye disease