News & Updates

Long-term isradipine does not prevent Parkinson’s disease progression

06 Apr 2020

Treatment with immediate-release isradipine, a dihydropyridine calcium-channel blocker, for 36 months has failed to slow the progression of early-stage Parkinson’s disease (PD), according to a study.

Long-term isradipine does not prevent Parkinson’s disease progression

06 Apr 2020

Pioglitazone reduces CV events in T2D patients with CVD history

06 Apr 2020

Use of pioglitazone is associated with a reduced risk of major adverse cardiovascular events (MACE) and is recommended in patients with or at high risk of type 2 diabetes (T2D), particularly those with a history of established cardiovascular disease (CVD), suggests a study.

Pioglitazone reduces CV events in T2D patients with CVD history

06 Apr 2020

Indacaterol/glycopyrronium improves lung function, symptoms in LABD‐naïve COPD patients

06 Apr 2020 by

Treatment with indacaterol/glycopyrronium (IND/GLY) 110/50 μg once daily in patients with chronic obstructive pulmonary disease (COPD) who have not received long-acting bronchodilators (LABD) leads to improvements in lung function, daily symptoms, dyspnoea, health-related quality of life and rescue medication compared with use of long-acting muscarinic antagonists (LAMA), a study has shown.

Indacaterol/glycopyrronium improves lung function, symptoms in LABD‐naïve COPD patients

06 Apr 2020

Lower on par with standard glucose treatment threshold for neonatal hypoglycaemia

06 Apr 2020 by

In the management of infants born with moderate hypoglycaemia, a strategy of initiating treatment at a lower glucose concentration proves noninferior to a traditional threshold of 47 mg/dL in terms of preventing brain injury, according to the results of the HypoEXIT* trial.

Lower on par with standard glucose treatment threshold for neonatal hypoglycaemia

06 Apr 2020

Is lopinavir-ritonavir effective against severe COVID-19?

05 Apr 2020

Treatment with lopinavir-ritonavir in addition to standard care appears to have no clear benefit in hospitalized adult patients with severe coronavirus disease (COVID-19), reveals a study.

Is lopinavir-ritonavir effective against severe COVID-19?

05 Apr 2020

RESONATE-2: Ibrutinib benefits in older CLL/SLL patients sustained at 5 years

04 Apr 2020 by

The single-agent ibrutinib demonstrates significant and durable survival benefits compared with chlorambucil in the first-line treatment of older patients with chronic lymphocytic leukaemia (CLL)/small lymphocytic lymphoma (SLL), including those with high-risk prognostic features, according to 5-year data from the RESONATE-2 study.

RESONATE-2: Ibrutinib benefits in older CLL/SLL patients sustained at 5 years

04 Apr 2020

Pinaverium bromide plus simethicone improves abdominal pain, bloating in IBS

03 Apr 2020 by

The combination of pinaverium bromide 100 mg plus simethicone 300 mg is effective in the treatment of bloating (PB+S) and abdominal pain in patients with active irritable bowel syndrome (IBS), a study has shown. The effect of combined therapy on the frequency of stool consistency was significant in IBS with constipation (C) and mixed-type (M) IBS.

Pinaverium bromide plus simethicone improves abdominal pain, bloating in IBS

03 Apr 2020

Low-dose alteplase during PCI increases microvascular obstruction in STEMI patients

03 Apr 2020

Adjunctive treatment with low-dose intracoronary alteplase during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) and an ischaemic time ≥4 to 6 h results in increased microvascular obstruction (MVO), a study has shown. Intracoronary alteplase appears to be unsafe for this subgroup.

Low-dose alteplase during PCI increases microvascular obstruction in STEMI patients

03 Apr 2020

Neonatal BCG shots lower mortality in TB-exposed, unexposed kids

03 Apr 2020

Neonatal BCG vaccination appears to reduce mortality both in tuberculosis (TB)-exposed and TB-unexposed children, according to a study, suggesting that timing of BCG administration factors in all-cause mortality.

Neonatal BCG shots lower mortality in TB-exposed, unexposed kids

03 Apr 2020

Block-replace ATD regimen prevents Graves’ disease relapse better than titration regimen

03 Apr 2020

In patients with Graves’ disease (GD), the block-replace antithyroid drug (ATD) regimen leads to a lower relapse rate than the titration regimen, according to a study. Factors such as younger age, larger goiter size or thyroid volume, and the higher free triiodothyronine or free thyroxine levels in the diagnosing phase are tied to a higher risk of relapse.

Block-replace ATD regimen prevents Graves’ disease relapse better than titration regimen

03 Apr 2020

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Long-term isradipine does not prevent Parkinson’s disease progression

Long-term isradipine does not prevent Parkinson’s disease progression

Pioglitazone reduces CV events in T2D patients with CVD history

Pioglitazone reduces CV events in T2D patients with CVD history

Indacaterol/glycopyrronium improves lung function, symptoms in LABD‐naïve COPD patients

Indacaterol/glycopyrronium improves lung function, symptoms in LABD‐naïve COPD patients

Lower on par with standard glucose treatment threshold for neonatal hypoglycaemia

Lower on par with standard glucose treatment threshold for neonatal hypoglycaemia

Is lopinavir-ritonavir effective against severe COVID-19?

Is lopinavir-ritonavir effective against severe COVID-19?

RESONATE-2: Ibrutinib benefits in older CLL/SLL patients sustained at 5 years

RESONATE-2: Ibrutinib benefits in older CLL/SLL patients sustained at 5 years

Pinaverium bromide plus simethicone improves abdominal pain, bloating in IBS

Pinaverium bromide plus simethicone improves abdominal pain, bloating in IBS

Low-dose alteplase during PCI increases microvascular obstruction in STEMI patients

Low-dose alteplase during PCI increases microvascular obstruction in STEMI patients

Neonatal BCG shots lower mortality in TB-exposed, unexposed kids

Neonatal BCG shots lower mortality in TB-exposed, unexposed kids

Block-replace ATD regimen prevents Graves’ disease relapse better than titration regimen

Block-replace ATD regimen prevents Graves’ disease relapse better than titration regimen