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Does ribavirin improve efficacy of SOF/VEL/VOX in HCV retreatment?

24 Jul 2023 by

The combination of sofosbuvir, velpatasvir, and voxilaprevir (SOF/VEL/VOX) with or without ribavirin demonstrates efficacy for the retreatment of patients with hepatitis C virus (HCV) infection in whom prior direct-acting antiviral (DAA) treatment has failed, a study in Egypt has shown.

Does ribavirin improve efficacy of SOF/VEL/VOX in HCV retreatment?

24 Jul 2023

Small vessel disease progression ups dementia risk

24 Jul 2023

A study with 14-year follow-up has pointed to baseline small vessel disease (SVD) severity and SVD progression as independent predictors of dementia.

Small vessel disease progression ups dementia risk

24 Jul 2023

Pooled analysis reinforce voclosporin potential for lupus nephritis

24 Jul 2023 by

In a pooled, post hoc analysis of the AURA-LV and AURORA 1 studies, lupus nephritis (LN) patients with moderate-to-high baseline levels of proteinuria (UPCR* ≥2 to ≥3 mg/mg) who were receiving add-on voclosporin achieved higher renal response rates and earlier UPCR reductions vs those who were only treated with the control regimen.

Pooled analysis reinforce voclosporin potential for lupus nephritis

24 Jul 2023

Boys with T1DM now hit puberty early

24 Jul 2023

For a significant number of boys with type 1 diabetes mellitus (T1DM), puberty may start early than it used to, as reported in a study for Greece.

Boys with T1DM now hit puberty early

24 Jul 2023

Social determinants of health explain disparities in mental health of older adults

23 Jul 2023

Differences in social determinants of health (SDoH) tend to trigger racial/ethnic disparities in psychological health and well-being among older adults, suggests a study. Key SDoH include education, income, number of years worked, and insurance parity.

Social determinants of health explain disparities in mental health of older adults

23 Jul 2023

Prolonged-release pirfenidone shows therapeutic potential in post–COVID-19 pulmonary fibrosis

22 Jul 2023

A 3-month course of prolonged-release pirfenidone formulation appears to be safe and efficacious in the treatment of patients with postacute sequelae of COVID-19 (PASC)-pulmonary fibrosis, as shown in a study.

Prolonged-release pirfenidone shows therapeutic potential in post–COVID-19 pulmonary fibrosis

22 Jul 2023

Type 2 diabetes: Semaglutide pill works just as well as injectable

22 Jul 2023 by

Treatment with either oral or subcutaneous semaglutide yields favourable outcomes for patients with type 2 diabetes (T2D), according to real-world data.

Type 2 diabetes: Semaglutide pill works just as well as injectable

22 Jul 2023

Trimethylamine-N-oxide levels linked to stroke risk

22 Jul 2023

The gut microbiota-derived metabolite trimethylamine-N-oxide (TMAO) is significantly associated with the risk of stroke, according to a study.

Trimethylamine-N-oxide levels linked to stroke risk

22 Jul 2023

Low-dose vaginal misoprostol best approach for outpatient cervical ripening

22 Jul 2023

For outpatient cervical ripening and labour induction, low-dose vaginal misoprostol has the most favourable risk-benefit profile, reducing the interval to delivery, according to the results of a systematic review and network meta-analysis.

Low-dose vaginal misoprostol best approach for outpatient cervical ripening

22 Jul 2023

Semaglutide, insulin degludec sustain glycaemic control in patients with T2D

22 Jul 2023 by

Treatment with once-weekly subcutaneous semaglutide and once-daily insulin degludec sustained an HbA_1c level of ≤7.5 percent in individuals with adequately controlled type 2 diabetes (T2D) who were on multiple daily injections of insulin (MDI) regimen, according to the TRANSITION-T2D study presented at ADA 2023.

Semaglutide, insulin degludec sustain glycaemic control in patients with T2D

22 Jul 2023

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Does ribavirin improve efficacy of SOF/VEL/VOX in HCV retreatment?

Does ribavirin improve efficacy of SOF/VEL/VOX in HCV retreatment?

Small vessel disease progression ups dementia risk

Small vessel disease progression ups dementia risk

Pooled analysis reinforce voclosporin potential for lupus nephritis

Pooled analysis reinforce voclosporin potential for lupus nephritis

Boys with T1DM now hit puberty early

Boys with T1DM now hit puberty early

Social determinants of health explain disparities in mental health of older adults

Social determinants of health explain disparities in mental health of older adults

Prolonged-release pirfenidone shows therapeutic potential in post–COVID-19 pulmonary fibrosis

Prolonged-release pirfenidone shows therapeutic potential in post–COVID-19 pulmonary fibrosis

Type 2 diabetes: Semaglutide pill works just as well as injectable

Type 2 diabetes: Semaglutide pill works just as well as injectable

Trimethylamine-N-oxide levels linked to stroke risk

Trimethylamine-N-oxide levels linked to stroke risk

Low-dose vaginal misoprostol best approach for outpatient cervical ripening

Low-dose vaginal misoprostol best approach for outpatient cervical ripening

Semaglutide, insulin degludec sustain glycaemic control in patients with T2D

Semaglutide, insulin degludec sustain glycaemic control in patients with T2D