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Rucaparib improves rPFS vs docetaxel or 2nd-generation ARPI in BRCA-mutated mCRPC
Rucaparib significantly improves radiographic progression-free survival (rPFS) vs physician’s choice of docetaxel, abiraterone acetate or enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC) harbouring BRCA alterations whose disease has progressed after treatment with a second-generation androgen-receptor pathway inhibitor (ARPI), results of the phase III TRITON3 trial have shown.
Rucaparib improves rPFS vs docetaxel or 2nd-generation ARPI in BRCA-mutated mCRPC
06 Mar 2023Neoadjuvant immunotherapy delivers in cisplatin-ineligible bladder cancer
The use of pembrolizumab in the neoadjuvant setting appears to be associated with a higher rate of downstaging and a survival advantage among patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based neoadjuvant chemotherapy, according to a study presented at this year’s ASCO Genitourinary Cancers Symposium.
Neoadjuvant immunotherapy delivers in cisplatin-ineligible bladder cancer
03 Mar 2023Nivolumab plus cabozantinib superior to sunitinib in renal cell carcinoma
First-line treatment of advanced renal cell carcinoma (aRCC) with nivolumab plus cabozantinib (N+C) results in sustained survival and response benefits at 3 years minimum follow-up, which is consistent with previous follow-ups, according to a study presented at the 2023 ASCO GU Cancers Symposium.
Nivolumab plus cabozantinib superior to sunitinib in renal cell carcinoma
03 Mar 2023Final PROpel data confirm OS advantage with abiraterone plus olaparib
The combination of olaparib plus abiraterone in the first-line treatment of metastatic castration-resistant prostate cancer (mCRPC) appears to show a consistent trend toward overall survival (OS) benefit, according to the results of the final prespecified analysis of the phase III PROpel study presented at ASCO GU 2023.
Final PROpel data confirm OS advantage with abiraterone plus olaparib
01 Mar 2023Use of biomarkers, biologics ups success rate of clinical trials in gastric cancer
Success rates of clinical trials in gastric cancer tend to improve with the use of implementing biomarkers, receptor-targeted therapies, and biologics in clinical development, suggests a recent study.
Use of biomarkers, biologics ups success rate of clinical trials in gastric cancer
01 Mar 2023Zinc supplements may improve survival in nonmetastatic prostate cancer
Postdiagnostic use of low-dose zinc supplement may help reduce the risk of lethal prostate cancer and all-cause mortality among patients with nonmetastatic prostate cancer, suggests a recent study.