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Nirmatrelvir-ritonavir cuts disease progression, viral load in unvaccinated COVID-19 outpatients
In the phase II/III EPIC-HR* trial, the novel oral antiviral nirmatrelvir-ritonavir reduced the risk of progression of COVID-19 to severe disease, as well as viral load, in symptomatic, high-risk, unvaccinated nonhospitalized adults confirmed to have SARS-CoV-2 infection.
Nirmatrelvir-ritonavir cuts disease progression, viral load in unvaccinated COVID-19 outpatients
04 May 2022Narrow- vs broad-spectrum antibiotics: Which is better for older AECOPD patients?
Use of either empiric broad- or narrow-spectrum antibiotics in older patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) shows no remarkable difference in the primary outcome, reports a recent study.
Narrow- vs broad-spectrum antibiotics: Which is better for older AECOPD patients?
03 May 2022Progressive phenotype predicts transplantation-free survival in ILD, IPF patients
Nearly one in four nonidiopathic pulmonary fibrosis (non-IPF) patients with a fibrosing form of interstitial lung disease (FILD) develop a progressive phenotype relative to almost 60 percent of IPF patients, reveals a study. Survival of non-IPF FILD patients with such phenotype is similar to IPF.
Progressive phenotype predicts transplantation-free survival in ILD, IPF patients
02 May 2022Annual flu jab in HF patients may lower hospitalization, pneumonia risk
An annual influenza vaccination does not lower the risk of cardiovascular (CV) outcomes in patients with heart failure (HF), though it may reduce the risk of pneumonia and hospitalization, according to results of the IVVE study presented at ACC.22.
Annual flu jab in HF patients may lower hospitalization, pneumonia risk
27 Apr 2022Prolonged QTc in hospitalized COVID-19 patients tied to increased mortality risk
Prolonged corrected QT interval (QTc), as determined via electrocardiogram (ECG), may indicate an elevated risk of myocardial injury and death in patients hospitalized for COVID-19, according to a prospective study from Israel presented at EHRA 2022.
Prolonged QTc in hospitalized COVID-19 patients tied to increased mortality risk
25 Apr 2022Furmonertinib emerges as potential first-line option for EGFRm NSCLC
Treatment-naïve patients with locally advanced or metastatic EGFR-mutated (EGFRm) non-small-cell lung cancer (NSCLC) experience improved progression-free survival (PFS) when treated with furmonertinib compared with gefitinib, according to results of the phase III FURLONG study.
Furmonertinib emerges as potential first-line option for EGFRm NSCLC
22 Apr 2022SPOTLIGHT: Durvalumab shines in real-world trial on NSCLC
Findings from the SPOTLIGHT trial have shown the efficacy of administering durvalumab after chemoradiotherapy (CRT) in patients with unresectable stage III non-small-cell lung cancer (NSCLC).