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S-1 plus oxaliplatin on par with existing regimen for colorectal cancer treatment
Treatment with S-1, an oral fluoropyrimidine formulation similar to capecitabine, plus oxaliplatin (SOX) results in substantial improvements in overall response rate relative to capecitabine plus oxaliplatin (CapeOx) in patients with metastatic colorectal cancer, according to a Philippines study presented at the recent ESMO GI 2023.
S-1 plus oxaliplatin on par with existing regimen for colorectal cancer treatment
15 Aug 2023
Risk of hypertension higher with DTG in PLWH
In the secondary analysis of the NAMSAL and ADVANCE trials, first-line treatment with dolutegravir (DTG) was associated with significantly higher risks of treatment-emergent hypertension in people living with HIV (PLWH), especially in combination with tenofovir alafenamide (TAF).
Risk of hypertension higher with DTG in PLWH
15 Aug 2023
Another win for donanemab in TRAILBLAZER Alzheimer’s trial
In the phase III TRAILBLAZER-ALZ 2 study, donanemab significantly slowed clinical progression in individuals with early symptomatic Alzheimer’s disease* (AD) with amyloid and tau pathologies, demonstrating an important replication of the phase II findings.
Another win for donanemab in TRAILBLAZER Alzheimer’s trial
14 Aug 2023
Brain stimulation helps with Parkinson's disease-related walking problems
Delivering electrical stimulation over the cerebellum appears to improve gait disturbances in patients with Parkinson’s disease (PD) and help them walk better, as reported in a study from Japan.
Brain stimulation helps with Parkinson's disease-related walking problems
13 Aug 2023
Febuxostat vs benzbromarone: Which is more effective in CKD with hyperuricaemia, hypertension?
Treatment with either febuxostat or benzbromarone results in comparable outcomes among patients with stage G3 chronic kidney disease (CKD) with asymptomatic hyperuricaemia and hypertension, a study has shown.
Febuxostat vs benzbromarone: Which is more effective in CKD with hyperuricaemia, hypertension?
13 Aug 2023
Progesterone may raise chances of having a baby for couples with unexplained infertility
Couples with unexplained infertility who are seeking parenthood may benefit from progesterone treatment, which can increase the livebirth rates and decrease miscarriage rates by twofold, according to data from the PiNC* trial.
