News &amp; Updates

In women with newly diagnosed, advanced* ovarian cancer and a BRCA mutation**, the progression-free survival (PFS) benefit with maintenance olaparib was sustained beyond end of treatment, according to the 5-year follow-up results of the SOLO1 trial presented at SGO 2021.

Maintenance olaparib prolongs survival in ovarian cancer

Smart scales miss mark on fat, muscle mass measurements

Smart scales are not accurate for body composition measurements, consistently underestimating body fat mass and overestimating muscle mass, according to a recent study. For patient care, smart scale devices cannot replace the dual x-ray absorptiometry (DEXA) gold standard.

Smart scales miss mark on fat, muscle mass measurements

Serum neurofilament light chain levels help predict response to treatment in multiple sclerosis

Low baseline levels of serum neurofilament light chains (sNfL) may help identify multiple sclerosis (MS) patients who are likely to optimally respond to dimethyl fumarate (DMF) treatment, a recent study has found.

Serum neurofilament light chain levels help predict response to treatment in multiple sclerosis

Pneumonia hospitalization a risk factor for cardiac events

Hospitalization for pneumonia contributes to an increased risk of ischaemic cardiovascular disease in the short and long term among middle-aged and older adults, a study has found.

Pneumonia hospitalization a risk factor for cardiac events

Impaired fasting glucose, male sex up risk for diabetes in cancer patients

Some patients receiving chemotherapy with dexamethasone develop diabetes, and this risk is especially prominent in men and in the presence of impaired fasting glucose, according to a study.

Impaired fasting glucose, male sex up risk for diabetes in cancer patients

Single-dose BNT162b2 COVID-19 vaccine inadequate in cancer patients

One dose of the BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine yields poor efficacy in patients with solid or haematological cancer, but immunogenicity increases significantly in those with solid cancer following a second dose given on day 21 after the first dose, a prospective observational study has shown.

Single-dose BNT162b2 COVID-19 vaccine inadequate in cancer patients

Amphetamine patch for paediatric ADHD: Does evidence support its use?

An investigational transdermal amphetamine patch worn for 9 hours on the hip appeared effective in paediatric patients with attention deficit-hyperactivity disorder (ADHD) in a phase II, two-part trial.

Amphetamine patch for paediatric ADHD: Does evidence support its use?

More evidence needed for effectiveness of rights-based approach to girls’ sexual, reproductive health

Rights-based intervention seem to be effective at improving sexual and reproductive health among adolescent girls in low- and middle-income countries, a recent systematic review has found. However, the quality of evidence available is highly biased, underscoring the need for further, better-quality investigations.

More evidence needed for effectiveness of rights-based approach to girls’ sexual, reproductive health

Galcanezumab shows sustained efficacy, CV safety in migraine

05 May 2021 by

Not only does the CGRP* inhibitor galcanezumab show sustained efficacy in migraine patients, long-term treatment does not come with excess cardiovascular (CV) risk, according to studies presented at the AAN 2021 Annual Meeting.

Galcanezumab shows sustained efficacy, CV safety in migraine

Morphine drip delivers cardioprotection in acute myocardial infarction

05 May 2021 by

Administering intravenous morphine prior to primary percutaneous coronary intervention cuts myocardial and microvascular damage in patients with acute myocardial infarction (AMI), as shown in the MonAMI trial.

Morphine drip delivers cardioprotection in acute myocardial infarction