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PSA testing helps prevent prostate cancer deaths
A prostate specific antigen (PSA)-based screening is effective in significantly lowering the risk of death from prostate cancer (PC), reports a study. However, nonattendance, initiation after age 60 years, and discontinuation at age 70 years appear to increase such risk.
PSA testing helps prevent prostate cancer deaths
14 Jul 2022Disrupted gut fungi tied to colorectal cancer
Alterations in normal gut mycobiota profile, particularly the enrichment of the pathogenic Aspergillus rambellii, appear to aggravate the risk of colorectal cancer (CRC), according to a recent study.
Disrupted gut fungi tied to colorectal cancer
14 Jul 2022Panitumumab + mFOLFOX6 ups OS in 1L left-sided RAS wild-type mCRC in Japanese trial
Panitumumab plus modified FOLFOX6 (mFOLFOX6; fluorouracil, leucovorin, and oxaliplatin) as first-line therapy significantly improves overall survival (OS) vs bevacizumab plus mFOLFOX6 in patients with left-sided RAS wild-type (wt) metastatic colorectal cancer (mCRC), results of the Japanese PARADIGM trial have shown.
Panitumumab + mFOLFOX6 ups OS in 1L left-sided RAS wild-type mCRC in Japanese trial
14 Jul 2022Venetoclax-obinutuzumab ± ibrutinib induces PFS benefit in CLL
A time-limited regimen of venetoclax plus obinutuzumab with or without ibrutinib improved progression-free survival (PFS) in fit, treatment-naïve patients with chronic lymphocytic leukaemia (CLL), according to results of the phase III GAIA/CLL13 trial presented at EHA 2022.
Venetoclax-obinutuzumab ± ibrutinib induces PFS benefit in CLL
13 Jul 2022Can very low-risk breast cancer patients be spared from postop radiotherapy?
Adjuvant radiotherapy (RT) may be omitted in women with very low-risk breast cancer who have had breast conserving surgery (BCS) and have been receiving endocrine therapy, according to findings from the LUMINA study.
Can very low-risk breast cancer patients be spared from postop radiotherapy?
12 Jul 2022Sabizabulin for metastatic castration-resistant prostate cancer clears phase early trial
The oral cytoskeleton disruptor sabizabulin shows antitumour activity in men with metastatic castration-resistant prostate cancer, while having a favourable safety profile, as shown in the results of a phase Ib/II trial.