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The selective serotonin reuptake inhibitor escitalopram holds promise in the prevention of Alzheimer’s disease, reducing amyloid-β-42 levels in cerebrospinal fluid and brain tissue in older adults with normal cognitive function, according to recent evidence.
Patients with acute ischaemic stroke undergoing endovascular treatment are at heightened risk of poor functional outcome and symptomatic intracranial haemorrhage (sICH) in the presence of hyperglycaemia at admission, a study has found.
Survivors of stroke with premorbid depression and diabetes mellitus may fare badly, being at increased risk of loss of independence and dementia, according to a study.
Subjective cognitive decline (SCD) or anxiety symptoms in older individuals are independently associated with an increased risk of mild cognitive impairment (MCI) or dementia, a recent study has shown.
Crushing prasugrel tablets and administering it as a powder to patients with ST-segment elevation myocardial infarction (STEMI) prior to percutaneous coronary intervention (PCI) enhances the potency of platelet inhibition but fails to improve early coronary reperfusion, as shown in the results of the COMPARE CRUSH trial.
Chronic pain patients show high degrees of interest in nonpharmacological, behavioural interventions to their condition, a recent study has found. This interest is even greater among patients whose doctors recommended these treatments.
Cupping seems to help ease short-term pain intensity and disability, reports a recent meta-analysis, although further studies are needed due to high clinical heterogeneity and risks of bias in the existing literature.
Frail elderly adults undergoing vascular surgery are more likely to develop hospital-acquired geriatric syndromes, such as delirium, a recent study has found.
Older patients with neurodegenerative diseases frequently develop epilepsy, especially those with a history of depression, traumatic brain injury, or stroke, a study has found.
Childhood epilepsy carries an increased risk of self-harm in children, teens, and young adults, as suggested in a study.