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HBV suppressed on long-term tenofovir alafenamide; switch from TDF improves safety

14 Nov 2020 by

Tenofovir alafenamide (TAF) keeps chronic hepatitis B virus (HBV) in check through 5 years of treatment, with an added benefit of improving bone and kidney safety outcomes in patients who have switched from tenofovir disoproxil fumarate (TDF), according to data from two ongoing phase III studies.

HBV suppressed on long-term tenofovir alafenamide; switch from TDF improves safety

14 Nov 2020

N-acetylcysteine prevents neurotoxicity in colorectal, gastric cancer patients

13 Nov 2020

N-acetylcysteine provides a protective effect on chemotherapy-induced neuropathy by reducing its incidence and delaying its occurrence in patients with gastric or colorectal cancers, a study has shown.

N-acetylcysteine prevents neurotoxicity in colorectal, gastric cancer patients

13 Nov 2020

Seronegative AAG more common in older patients

08 Nov 2020

Older patients of autoimmune atrophic gastritis (AAG) tend to be seronegative for its hallmark biomarker, antiparietal cell antibodies (anti-PCA), a recent study has found.

Seronegative AAG more common in older patients

08 Nov 2020

$Sleeve gastrectomy beats RYGB in reducing fracture risk in obese patients$

Sleeve gastrectomy beats RYGB in reducing fracture risk in obese patients

06 Nov 2020 by

Patients with severe obesity who underwent sleeve gastrectomy (SG) had a significantly lower risk of fracture compared with those who underwent Roux-en-Y gastric bypass (RYGB) and those who did not undergo surgery, according to a recent study.

Sleeve gastrectomy beats RYGB in reducing fracture risk in obese patients

06 Nov 2020

Faecal test as good as colonoscopy in detecting CRC

05 Nov 2020 by

A faecal immunochemical test (FIT) is able to accurately rule out colorectal cancer (CRC) and is as sensitive as colonoscopy, the current gold standard for CRC diagnosis, the NICE* FIT study has shown.

Faecal test as good as colonoscopy in detecting CRC

05 Nov 2020

Presurgical IV iron does not PREVENTT post-surgical mortality in anaemic patients

03 Nov 2020 by

An intravenous (IV) iron infusion before major open abdominal surgery does not reduce the risk of post-surgical mortality or need for blood transfusion in anaemic patients, according to the UK-based PREVENTT* trial.

Presurgical IV iron does not PREVENTT post-surgical mortality in anaemic patients

03 Nov 2020

Regular use of reflux drug can lead to diabetes

03 Nov 2020 by

Proton pump inhibitor has an irreplaceable role in the treatment of acid-related disorders, but prolonged use of the drug has been shown to bring a host of illnesses, and this time it is type 2 diabetes.

Regular use of reflux drug can lead to diabetes

03 Nov 2020

Pertuzumab added to chemo-trastuzumab improved pCR in patients with HER2+ gastric cancer

03 Nov 2020 by

The addition of pertuzumab to standard perioperative chemotherapy (CT) comprising FLOT* and trastuzumab led to a significant improvement in pathologic complete response (pCR) in patients with HER2+ resectable oesophagogastric adenocarcinoma – at the expense however of higher toxicity rates, results of the phase II/III PETRARCA/FLOT 6 trial have shown.

Pertuzumab added to chemo-trastuzumab improved pCR in patients with HER2+ gastric cancer

03 Nov 2020

Thiopurine effective for long-term use in ulcerative colitis but less so in Crohn’s disease

03 Nov 2020

Thiopurine appears beneficial for long-term treatment of patients with ulcerative colitis (UC) but not for those with Crohn’s disease (CD) especially where there is perianal involvement, a study has found.

Thiopurine effective for long-term use in ulcerative colitis but less so in Crohn’s disease

03 Nov 2020

Common features, outcomes of CD complicated by upper gastrointestinal tract strictures

03 Nov 2020

Most of the upper gastrointestinal tract (UGT) strictures complicating Crohn’s disease (CD) occur in the duodenum and require surgical treatment, a recent study has found.

Common features, outcomes of CD complicated by upper gastrointestinal tract strictures

03 Nov 2020

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HBV suppressed on long-term tenofovir alafenamide; switch from TDF improves safety

HBV suppressed on long-term tenofovir alafenamide; switch from TDF improves safety

N-acetylcysteine prevents neurotoxicity in colorectal, gastric cancer patients

N-acetylcysteine prevents neurotoxicity in colorectal, gastric cancer patients

Seronegative AAG more common in older patients

Seronegative AAG more common in older patients

Sleeve gastrectomy beats RYGB in reducing fracture risk in obese patients

Sleeve gastrectomy beats RYGB in reducing fracture risk in obese patients

Faecal test as good as colonoscopy in detecting CRC

Faecal test as good as colonoscopy in detecting CRC

Presurgical IV iron does not PREVENTT post-surgical mortality in anaemic patients

Presurgical IV iron does not PREVENTT post-surgical mortality in anaemic patients

Regular use of reflux drug can lead to diabetes

Regular use of reflux drug can lead to diabetes

Pertuzumab added to chemo-trastuzumab improved pCR in patients with HER2+ gastric cancer

Pertuzumab added to chemo-trastuzumab improved pCR in patients with HER2+ gastric cancer

Thiopurine effective for long-term use in ulcerative colitis but less so in Crohn’s disease

Thiopurine effective for long-term use in ulcerative colitis but less so in Crohn’s disease

Common features, outcomes of CD complicated by upper gastrointestinal tract strictures

Common features, outcomes of CD complicated by upper gastrointestinal tract strictures