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Urinary proadrenomedullin predicts severity of community-acquired pneumonia in children
Urinary proadrenomedullin (proADM)/creatinine (Cr) ratio measured at the time of emergency department visit appears predictive of the development of severe outcomes in children with community-acquired pneumonia (CAP), with stronger discriminatory performance in radiographic disease, suggests a recent study.

Child abuse increased during COVID-19 lockdown
Child abuse rates appear to have increased during the lockdowns imposed to control COVID-19 transmission, according to a study from the US presented at the 2021 American Academy of Pediatrics National Conference & Exhibition (AAP 2021).

Childhood cancers often misdiagnosed as TB, leads to more deaths
Cancer is frequently misdiagnosed as tuberculosis (TB) in children due to the clinical and radiologic overlap of the two diseases, which then contributes to increased mortality in this population, reveals a recent study.

Repurposing a broad-spectrum antiviral drug may help treat asymptomatic, mild COVID-19
The oral antiviral drug umifenovir, which is used to treat influenza, appears to be beneficial in COVID-19 patients who are asymptomatic or with mild symptoms, with a phase III study showing that the drug is well tolerated and can induce viral clearance within 5 days.

Convalescent plasma ineffective for COVID-19
A recent Singapore meta-analysis of randomized controlled trials (RCT) has found no clear clinical benefit to using convalescent plasma (CP) for patients with the coronavirus disease 2019 (COVID-19), especially in those with severe disease.

Suboptimal influenza vaccination persists among insurance holders despite no copayment
The coverage of influenza vaccination for Medicare beneficiaries remains poor, reports a study, noting missed opportunities despite availability of vaccines with no copayment. In addition, there are still disparities in vaccination uptake by race/ethnicity.



