News & Updates
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Obesity, prediabetes up risk of diabetes in statin-treated PWH
People living with HIV (PWH) on statin therapy who have certain metabolic risk factors, such as obesity and prediabetes, are at greater risk of developing diabetes mellitus (DM), reports a study. This association is also present in those treated with placebo.
Happiness is key to a healthy heart
An analysis using the UK Biobank dataset shows a robust inverse association between well-being and risk of cardiovascular diseases (CVDs), underpinning the protective effect of higher well-being on the four major CVDs evaluated: coronary heart disease, MI, heart failure (HF), and stroke.
FASN inhibitor for MASH with fibrosis gets a pass to phase III
The oral fatty acid synthase (FASN) inhibitor denifanstat appears to produce meaningful improvements in metabolic dysfunction-associated steatohepatitis (MASH) and stage 2–3 fibrosis, as shown in the results of a phase IIb trial.
Insulin resistance linked to future hypertension in normotensive salt-sensitive individuals
A 10-year study has found the association of salt sensitivity with insulin resistance and endothelial dysfunction in the offspring of hypertensive salt-sensitive parents, making them susceptible to developing hypertension.
Survodutide safe to use in cirrhosis patients
Treatment with survodutide, which has previously shown its efficacy in reducing body weight and glycaemia in people with obesity or type 2 diabetes, is well tolerated by patients with compensated or decompensated cirrhosis, reports a study.