News & Updates

Post hoc analyses using pooled data from the phase III LIBERTY-PN PRIME and PRIME2 trials showed that dupilumab improves disease-specific quality of life (QoL), itch, skin pain, and sleep in adult patients with prurigo nodularis.

Concomitant administration of vancomycin and piperacillin/tazobactam appears to contribute to an increased risk of developing acute kidney injury in intensive care unit (ICU) patients, particularly those with normal kidney function and who require longer therapy durations, according to a retrospective study.

Chemotherapy appears to confer survival advantage in patients with appendix adenocarcinoma who have node-positive tumours, according to a study presented at ESMO Sarcoma 2023.

In neonates with congenital diaphragmatic hernia, early treatment with prostacyclin appears to reduce the need for extracorporeal life support in the postnatal period, according to a study.

Use of antiosteoporotic medication, particularly a long-acting regimen, appears to reduce postfracture mortality, according to a population-based study.

Treatment with the investigational, topical pan-JAK inhibitor delgocitinib cream led to significantly greater improvements in efficacy outcomes compared with the vehicle cream in moderate-to-severe chronic hand eczema (CHE) in the pivotal phase III DELTA 1 trial, offering a rational strategy for targeted therapy.