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Large UK study underpins role of COVID-19 vax in mental illness
In a cohort study of over 18 million individuals with up to 2 years of follow-up, the incidences of most mental illnesses were markedly elevated following COVID-19 diagnosis compared with before or without COVID-19, particularly among the unvaccinated and before COVID-19 vaccines became available.

Many Singaporeans suffer from undiagnosed, undertreated allergic rhinitis
A substantial number of allergic rhinitis (AR) cases in Singapore, particularly those with more severe symptoms, remain undiagnosed or receive inadequate treatment. This contributes to a hidden but significant burden of AR in the population, as shown in a study.

Chronic bronchitis symptoms hint at benefits of mepolizumab in COPD with T2 inflammation
The presence of chronic bronchitis symptoms in COPD with T2 inflammation drives a more pronounced and significant benefit from mepolizumab in terms of reducing CAT scores, as shown in a post hoc analysis pooling data from two phase III trials — METREX and METREO

Long-term benefits with molnupiravir modest at best in COVID-19 treatment
The antiviral molnupiravir confers continued but modest benefits in terms of reducing COVID-19–related symptoms up to 6 months after the index infection in a vaccinated population, according to a secondary analysis of the PANORAMIC trial.

What fuels flu, pneumococcal vaccine hesitancy in SG?
In Singapore, influenza and pneumococcal vaccination coverage remains stubbornly low. Results of two separate analysis of a cross-sectional survey shed light on this concerning trend, highlighting the roles of vaccine knowledge and attitude, healthcare professionals, and social support in influencing vaccination decisions.



