News & Updates

As a first-line antiseizure medication (ASM) for infants, levetiracetam (LEV) is potentially noninferior to phenobarbital (PB) and shows a more acceptable safety profile, a new study has found.

The use of kisspeptin appears to restore sexual and facial attraction brain processing in premenopausal women with hypoactive sexual desire disorder, without an accompanying increase in the risk of adverse effects, a study has found.

New drug applications approved by US FDA as of 16 - 31 October 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

The diagnosis and treatment of multidrug-resistant (MDR) gram-negative bacteria in critically ill patients present many clinical challenges. Selection of appropriate antibiotic therapy in a timely manner requires patients’ comprehensive medical history, updated local knowledge of microbiological epidemiology, efficient use of diagnostic tools, and balancing of information from clinical trial data, real-world evidence (RWE), and guidelines.

In a symposium Pfizer organized in conjunction with the Asia Pacific Intensive Care Symposium (APICS), Professor David Paterson from the National University of Singapore discussed the importance of RWE in the antibiotic armamentarium, using ceftazidime-avibactam (CAZ-AVI, Zavicefta^®) as an example. Dr Asok Kurup, Consultant Infectious Diseases Physician at Mount Elizabeth Medical Centre, Singapore, explained how rapid diagnostics can guide treatment choices to improve patient outcomes in MDR gram-negative infections.