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Patients upset by frequent side effects of RA drugs

Patients upset by frequent side effects of RA drugs

12 Sep 2022
Add-on pyrotinib in neoadjuvant setting safe, effective for HER2-positive advanced breast cancer

Add-on pyrotinib in neoadjuvant setting safe, effective for HER2-positive advanced breast cancer

12 Sep 2022

In the treatment of patients with HER2-positive locally advanced breast cancer, adding pyrotinib to trastuzumab plus chemotherapy in the neoadjuvant setting yields high response rates while being safe, according to the results of NeoATP trial.

Add-on pyrotinib in neoadjuvant setting safe, effective for HER2-positive advanced breast cancer

12 Sep 2022
STRIDE regimen benefit in unresectable HCC consistent across baseline liver function

STRIDE regimen benefit in unresectable HCC consistent across baseline liver function

11 Sep 2022
Trifluridine/tipiracil add-on to bevacizumab safe, effective for mCRC

Trifluridine/tipiracil add-on to bevacizumab safe, effective for mCRC

09 Sep 2022

In patients with metastatic colorectal cancer (mCRC), using trifluridine/tipiracil with bevacizumab is a safe and effective treatment for refractory disease, a recent study has found.

Trifluridine/tipiracil add-on to bevacizumab safe, effective for mCRC

09 Sep 2022
Low-dose methotrexate-related melanoma risk considered negligible

Low-dose methotrexate-related melanoma risk considered negligible

09 Sep 2022
CROWN: 1L lorlatinib improves PFS, reduces CNS progression in ALK-positive NSCLC ± brain metastases

CROWN: 1L lorlatinib improves PFS, reduces CNS progression in ALK-positive NSCLC ± brain metastases

09 Sep 2022 bySarah Cheung

First-line treatment of ALK-positive non-small-cell lung cancer (NSCLC) with lorlatinib improves progression-free survival (PFS) and reduces central nervous system (CNS) progression vs crizotinib, regardless of presence or absence of baseline brain metastases (BM), a post hoc analysis of the phase III CROWN trial has shown.

CROWN: 1L lorlatinib improves PFS, reduces CNS progression in ALK-positive NSCLC ± brain metastases

09 Sep 2022
Insulin glargine, degludec yield comparable effects on glycaemic control

Insulin glargine, degludec yield comparable effects on glycaemic control

09 Sep 2022

In patients with of type 2 diabetes (T2D), glargine 300 U/mL (Gla-300) and degludec 100 U/mL (Deg-100) deliver similar improvements in glycaemic control, without increasing weight and hypoglycaemic events over 6 months of treatment, according to data from the retrospective RESTORE-2 NAIVE study.

Insulin glargine, degludec yield comparable effects on glycaemic control

09 Sep 2022