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Netarsudil use for glaucoma may cause punctal stenosis
Use of topical netarsudil 0.02% for the treatment of glaucoma results in the development of reversible punctal stenosis, a recent study has found. This inflammation-mediated stenosis can cause tearing and related symptoms and may lead to treatment discontinuation with sufficient severity.

Updated ASCEMBL results boost asciminib potential for CML
In the week-96 analysis of the phase III ASCEMBL trial, the first BCR::ABL1 STAMP* inhibitor asciminib sustained superiority over bosutinib for individuals with CML-CP** who have failed ≥2 lines of prior tyrosine kinase inhibitors (TKIs).

Response analysis further establishes tezepelumab benefit in severe uncontrolled asthma
Adolescents and adults with severe uncontrolled asthma while on inhaled corticosteroids (ICS) had greater responses to the human monoclonal antibody tezepelumab than placebo, according to prespecified exploratory results of the phase III NAVIGATOR trial.

Infliximab, adalimumab biosimilars effective, safe in paediatric IBD
The use of biosimilars of infliximab (IFX) and adalimumab (ADA) is both safe and effective in children with inflammatory bowel disease (IBD), inducing high rates of failure-free survival with a low incidence of adverse events, according to a study presented at the 2022 Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN 2022).





