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Aspirin-statin combo lowers hepatocellular carcinoma incidence
Daily use of aspirin reduces the risk of incident hepatocellular carcinoma (HCC), while the combination of daily aspirin use and statin results in a lower incidence of HCC, which suggests a beneficial interaction, according to a study. In addition, no excess oesophageal variceal haemorrhage (VH) is seen among daily aspirin users compared with nonusers.

SARS-CoV-2 tied to increased obstetric-related morbidity, mortality
SARS-CoV-2 infection during pregnancy or the postpartum period is tied to an increased risk of maternal mortality or serious morbidity due to obstetric complications, a study from the US showed.

Mild chronic hypertension in pregnancy: BP-lowering treatment improves outcomes without harm
When it comes to treating mild chronic hypertension during pregnancy, a strategy of lowering blood pressure (BP) below 140/90 mm Hg is preferrable, as it leads to better pregnancy outcomes without increasing the risk of birthing small-for-gestational-age babies when compared with a strategy of reserving treatment only for severe hypertension, according to the open-label Chronic Hypertension and Pregnancy (CHAP) trial.

Semaglutide trumps liraglutide for weight loss in nondiabetic overweight or obese patients
Nondiabetic adults with overweight or obesity lost more weight when treated with once-weekly semaglutide than once-daily liraglutide, as demonstrated by results of the phase IIIb STEP* 8 trial.

Add-on amantadine lessens “off” episodes in Parkinson’s disease
A delayed release/extended release (DR/ER) formulation of amantadine can help reduce breakthrough symptoms in Parkinson’s disease patients when the effect of levodopa therapy wears off, as shown in a recent study.




