News & Updates

Metformin treatment discontinuation has been found to lead to increased incidence of dementia among older adults, and this association cannot be explained by changes in glucose control or insulin use.

Chronic hepatitis B virus (HBV) infection appears to put Chinese adults at higher risk of intracerebral haemorrhage but not other stroke subtypes, as reported in a study.

Strawberries can potentially contribute to the prevention of dementia, with a small study suggesting that supplementation with whole-fruit strawberry powder helps improve memory in middle-aged adults.

A post hoc analysis of the CHANCE-2 randomized controlled trial (RCT) demonstrates that ticagrelor-aspirin combination therapy is associated with a significantly lower risk of new stroke within 90 days vs the clopidogrel-aspirin combination in Chinese CYP2C19 loss‐of‐function allele carriers with minor stroke or transient ischaemic attack (TIA) without intracranial artery stenosis (ICAS).

Neural control of a robotic ankle prosthesis appears to help its users to employ mechanisms that the body naturally uses to maintain balance and stability, including ankle movements, for better postural control, as shown in a study.

New drug applications approved by US FDA as of 16-31 October 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

A landmark study conducted in China and South Korea has demonstrated the effectiveness and safety of rimegepant – a groundbreaking orally administered calcitonin gene-related peptide (CGRP) antagonist – for the acute treatment of migraine among adults. [Lancet Neurol 2023;22:476-484] This phase III, double-blind, randomized, placebo-controlled trial marks the first clinical study of a gepant for migraine in China and South Korea, offering promising insights into migraine management.

Individuals with retinal artery occlusion (RAO) may be at increased risk of death, stroke, and myocardial infarction (MI) both in the short and long term, according to a study.

When added to standard care, early and empirical treatment with high-dose cryoprecipitate does not appear to improve clinical outcomes in patients with trauma and bleeding, according to the CRYOSTAT-2 study.