News & Updates

The combination of nivolumab (NIVO) with either chemotherapy (chemo) or ipilimumab (IPI) continues to confer overall survival (OS) benefit as first-line treatment for patients with advanced oesophageal squamous cell carcinoma (ESCC) compared with chemo alone, according to updated results of the CheckMate 648 trial presented at ASCO GI 2023.

A recent study has shown the safety of cold snare polypectomy (CSP) for the resection of ≤10 mm pedunculated polyps (PPs). In addition, CSP appears to contribute to a reduced risk of immediate bleeding relative to the common perception among gastroenterologists.

In the final surgical salvage results of the phase III OPERA* trial, boosting a neoadjuvant external beam chemoradiotherapy (EBCRT) regimen with contact X-ray brachytherapy (CXB) led to better organ preservation (OP) rates than with EB radiotherapy (EBRT) in individuals with rectal cancer.

An 8-week course of electroacupuncture appears to increase the frequency of spontaneous bowel movements and improve the quality of life in patients with cancer who are experiencing opioid-induced constipation, according to a study from China.

Endoscopic ultrasound (EUS)-guided through-the-needle biopsy (TTNB) and EUS-needle-based confocal laser endomicroscopy (nCLE) appear to be better options for centres with relevant expertise and facilities when diagnosing pancreatic cystic lesions (PCLs), suggests a study.

Relatives of patients with eosinophilic esophagitis (EoE) are at increased risk of developing eosinophilic gastritis/gastroenteritis (EG/EGE), according to a study, which suggests shared genetic factors among these eosinophilic gastrointestinal diseases (EGIDs).

Treatment with oral microbiome SER-109 in patients with recurrent Clostridioides difficile infection (CDI) is well tolerated and appears to reduce recurrence, as shown in a phase III ECOSPOR IV study.