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KEYNOTE-590 extended follow-up shows pembro + chemo maintains survival in advanced oesophageal cancer

12 Mar 2022 by

First-line treatment with pembrolizumab + chemotherapy maintains overall survival (OS) and progression-free survival (PFS) in patients with advanced or metastatic oesophageal cancer, according to an additional 12-month follow-up of the KEYNOTE-590* study presented at ASCO GI 2022.

KEYNOTE-590 extended follow-up shows pembro + chemo maintains survival in advanced oesophageal cancer

12 Mar 2022

Endovascular therapy has added value in patients with acute large vessel occlusion

11 Mar 2022 by

Endovascular therapy (EVT) in addition to medical therapy appeared to improve outcomes in patients with acute large vessel occlusion (LVO) with large ischaemic core following a stroke, according to results of the RESCUE-Japan LIMIT* trial.

Endovascular therapy has added value in patients with acute large vessel occlusion

11 Mar 2022

Anthropometric measurements at birth do not affect response to obesity treatment

11 Mar 2022

While neonatal anthropometric measures are related to the degree of obesity in childhood, it does not seem to affect response to multidisciplinary treatment to childhood obesity, a recent study has found.

Anthropometric measurements at birth do not affect response to obesity treatment

11 Mar 2022

FUT2 mutations tied to positive clinical course in Crohn’s disease

11 Mar 2022

An association exists between fucosyltransferase 2 (FUT2) mutation status and a favourable clinical course in Crohn’s disease (CD), reports a study.

FUT2 mutations tied to positive clinical course in Crohn’s disease

11 Mar 2022

Eating >3 eggs/week may lower bad cholesterol levels

11 Mar 2022 by

Individuals with chronic metabolic disorders who consume more than three eggs a week do not seem to have worse blood lipid parameters, according to a study. Among those without such conditions, consumption of more eggs even leads to a better lipid profile.

Eating >3 eggs/week may lower bad cholesterol levels

11 Mar 2022

Which melphalan formulation works better against engraftment syndrome?

11 Mar 2022

The incidence of engraftment syndrome (ES), a common complication of autologous haematopoietic cell transplantation (HCT), is comparable between melphalan formulations among patients with multiple myeloma and immunoglobulin light chain amyloidosis, reveals a study.

Which melphalan formulation works better against engraftment syndrome?

11 Mar 2022

Obinutuzumab + SoC improves renal responses in LN patients

11 Mar 2022 by

The addition of obinutuzumab, a humanized type II anti-CD20 monoclonal antibody that induces potent B-cell depletion, to a background of standard-of-care (SoC) therapy led to improved renal responses in patients with proliferative lupus nephritis (LN) compared with SoC alone, findings from the phase II NOBILITY trial have shown.

Obinutuzumab + SoC improves renal responses in LN patients

11 Mar 2022

Burnout a big problem among pharmacy technicians in SG

11 Mar 2022 by

Burnout is very common among pharmacy technicians (PT) in Singapore, and is driven mainly by heavy workload, poor social support, and low resilience, according to a recent study.

Burnout a big problem among pharmacy technicians in SG

11 Mar 2022

Rivaroxaban preserves renal function better than warfarin in NVAF patients

11 Mar 2022

In treating nonvalvular atrial fibrillation (NVAF) patients, rivaroxaban carries a lower risk of renal decline than warfarin, a recent study has found.

Rivaroxaban preserves renal function better than warfarin in NVAF patients

11 Mar 2022

Recent updates on HIV prevention and treatment in Singapore

11 Mar 2022

Human immunodeficiency virus (HIV) infection remains a public health priority in Singapore. The National Centre for Infectious Diseases (NCID) established the National HIV Programme (NHIVP) to coordinate the country-wide HIV response in collaboration with clinicians, healthcare professionals, public health practitioners, and other stakeholders. The NHIVP develops and updates evidence-based guidelines and best practices on HIV prevention, testing, and treatment. This article summarizes the best practices and key updates on prescribing of HIV pre-exposure prophylaxis (PrEP), and use of antiretroviral therapy (ART) in Singapore.

Recent updates on HIV prevention and treatment in Singapore

11 Mar 2022

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KEYNOTE-590 extended follow-up shows pembro + chemo maintains survival in advanced oesophageal cancer

KEYNOTE-590 extended follow-up shows pembro + chemo maintains survival in advanced oesophageal cancer

Endovascular therapy has added value in patients with acute large vessel occlusion

Endovascular therapy has added value in patients with acute large vessel occlusion

Anthropometric measurements at birth do not affect response to obesity treatment

Anthropometric measurements at birth do not affect response to obesity treatment

FUT2 mutations tied to positive clinical course in Crohn’s disease

FUT2 mutations tied to positive clinical course in Crohn’s disease

Eating >3 eggs/week may lower bad cholesterol levels

Eating >3 eggs/week may lower bad cholesterol levels

Which melphalan formulation works better against engraftment syndrome?

Which melphalan formulation works better against engraftment syndrome?

Obinutuzumab + SoC improves renal responses in LN patients

Obinutuzumab + SoC improves renal responses in LN patients

Burnout a big problem among pharmacy technicians in SG

Burnout a big problem among pharmacy technicians in SG

Rivaroxaban preserves renal function better than warfarin in NVAF patients

Rivaroxaban preserves renal function better than warfarin in NVAF patients

Recent updates on HIV prevention and treatment in Singapore

Recent updates on HIV prevention and treatment in Singapore