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Cenobamate cuts SUDEP risk

25 Jul 2025 by

A study presented at EAN 2025 demonstrates a reduction in the risk of sudden unexpected death in epilepsy (SUDEP) following treatment with the antiseizure medication (ASM) cenobamate among Spanish individuals in the phase III C021 study. The reductions were based on SUDEP-3 and SUDEP-7 risk scores.

Cenobamate cuts SUDEP risk

25 Jul 2025

Nerandomilast may slow lung function decline in idiopathic pulmonary fibrosis

25 Jul 2025

Treatment with nerandomilast helps preserve lung function in patients with idiopathic pulmonary fibrosis, as shown in the phase III FIBRONEER-IPF trial.

Nerandomilast may slow lung function decline in idiopathic pulmonary fibrosis

25 Jul 2025

Ivarmacitinib shows favourable risk–benefit profile in AD

24 Jul 2025

The selective oral Janus kinase 1 (JAK1) inhibitor ivarmacitinib helps improve the signs and symptoms of moderate-to-severe atopic dermatitis (AD) in adolescent and adult patients, while having a manageable safety profile, according to a phase III trial.

Ivarmacitinib shows favourable risk–benefit profile in AD

24 Jul 2025

Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

24 Jul 2025 by

New research from Singapore shows that individuals with a higher intake of ultraprocessed foods (UPF) during their midlife years are likely to have lower handgrip strength in later life.

Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

24 Jul 2025

BP status mediates link between kidney, vascular health biomarkers in young adults

24 Jul 2025

Mechanisms associated with early nephron-specific kidney injury biomarkers in young adults vary according to the blood pressure (BP) status, reports a study.

BP status mediates link between kidney, vascular health biomarkers in young adults

24 Jul 2025

How do parents perceive physical activity in children with cancer?

24 Jul 2025 by

The role of the family is critical to the encouragement of physical activity (PA) among childhood cancer survivors (CCS), according to a Singapore study. Apart from individuals and families, the community and society can also influence participation in PA.

How do parents perceive physical activity in children with cancer?

24 Jul 2025

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

24 Jul 2025

A recent phase III trial of NUC-1031/cisplatin has been terminated early due to ineffectiveness as first-line treatment for advanced biliary tract cancer (BTC).

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

24 Jul 2025

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

24 Jul 2025 by

Individuals with tardive dyskinesia (TD) report favourable outcomes with the VMAT2 inhibitor deutetrabenazine in an age subgroup analysis.

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

24 Jul 2025

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

24 Jul 2025

In the treatment of patients with relapsing polymyalgia rheumatica who have had an inadequate response to corticosteroids or who cannot tolerate corticosteroid taper, the use of sarilumab appears to produce clinically important improvements in health-related quality of life and patient-reported outcomes, according to the results of a phase III study.

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

24 Jul 2025

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

24 Jul 2025 by

The addition of pembrolizumab to chemotherapy with or without bevacizumab significantly improves progression-free survival (PFS) and overall survival (OS) in East Asian patients with persistent, recurrent or metastatic cervical cancer, according to an exploratory analysis of the final results from the phase III KEYNOTE-826 trial.

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

24 Jul 2025

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Cenobamate cuts SUDEP risk

Cenobamate cuts SUDEP risk

Nerandomilast may slow lung function decline in idiopathic pulmonary fibrosis

Nerandomilast may slow lung function decline in idiopathic pulmonary fibrosis

Ivarmacitinib shows favourable risk–benefit profile in AD

Ivarmacitinib shows favourable risk–benefit profile in AD

Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

BP status mediates link between kidney, vascular health biomarkers in young adults

BP status mediates link between kidney, vascular health biomarkers in young adults

How do parents perceive physical activity in children with cancer?

How do parents perceive physical activity in children with cancer?

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer