News &amp; Updates

The incidence rates of in-hospital cardiac arrest (IHCA) show a modest association with survival in older patients, reports a recent study, noting that IHCA incidence rates may be considered an independent quality metric.

IHCA incidence tied to survival in older patients

Optimal range of lithium serum levels for safer use in bipolar disorder

08 Jul 2025 by

Researchers from the University of Hong Kong (HKU) have identified lithium level thresholds associated with risks of hypothyroidism, hyperthyroidism, and stage ≥3 chronic kidney disease (CKD). This provides empirical evidence that can facilitate the development of clinical guidelines for lithium treatment in bipolar disorder.

Optimal range of lithium serum levels for safer use in bipolar disorder

08 Jul 2025

Linperlisib plus chidamide shows therapeutic potential in cutaneous T-cell lymphoma

Combination treatment with the PI3Kδ inhibitor linperlisib plus the histone deacetylase inhibitor chidamide has demonstrated promising clinical activity in relapsed or refractory cutaneous T-cell lymphoma (CTCL) in a phase I study.

Linperlisib plus chidamide shows therapeutic potential in cutaneous T-cell lymphoma

Patency capsule retention tied to small bowel disease in CD

In patients with Crohn’s disease (CD), retention of both patency capsules and video capsule endoscopy (VCE) is significantly associated with small bowel disease on imaging scans, suggests a study.

Patency capsule retention tied to small bowel disease in CD

Is cannabis protective against proliferative vitreoretinopathy after retinal detachment repair?

Cannabis users who underwent initial repair for retinal detachment (RD) appear to be at lower risk of developing proliferative vitreoretinopathy and, in turn, requiring subsequent complex RD repair when compared with their nonuser peers, according to a retrospective study.

Is cannabis protective against proliferative vitreoretinopathy after retinal detachment repair?

Delgocitinib cream safe, effective for long-term use in eczema

07 Jul 2025 by

Long-term treatment with delgocitinib is well-tolerated and raises no major safety concerns among patients with chronic hand eczema (CHE), results of the DELTA 3 trial have shown. Its use also maintains disease control for up to 52 weeks.

Delgocitinib cream safe, effective for long-term use in eczema

07 Jul 2025

Aspirin use may prevent CRC metastasis

The use of aspirin appears to provide protective benefits against metastasis in patients with colorectal cancer (CRC), reports a study.

Aspirin use may prevent CRC metastasis

Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

07 Jul 2025 by

LUT014 gel, a novel, small-molecule, topical formulation of a BRAF inhibitor, relieves acneiform rash toxicities from anti-EGFR therapies, findings from a phase II study suggest.

Topical BRAF inhibitor relieves EGFR-induced acneiform eruption

Malnutrition tied to depressive mood in older adults

Nutritional status may influence the mental health of older adults undergoing rehabilitation, reports a recent study. This association is mediated by muscle mass reduction and disease burden.

Malnutrition tied to depressive mood in older adults

Hormone therapy's impact on young-onset breast cancer risk varies by type

New research shows that using oestrogen hormone therapy alone may reduce the risk of young-onset breast cancer, while combining it with progestin could result in a risk increase among women with intact uterus and ovaries.

Hormone therapy's impact on young-onset breast cancer risk varies by type