News & Updates

In Singapore, the number of people assumed to be an organ donor sharply contrasts with the actual number of those willing to donate, and this discrepancy is driven by barriers related to emotions and culture or religion.

Use of a 4-factor prothrombin complex concentrate (4F-PCC) for oral factor Xa (FXa) inhibitor-related acute major bleeding appears to work for most patients, results of a recent study have shown.

It is rare to achieve successful home noninvasive ventilation (NIV) in real life, reports a recent study. To improve patient-centred outcomes, health-related quality of life (HRQOL) and NIV tolerance must then be assessed.

In patients with untreated acute myeloid leukaemia (AML) ineligible for intensive chemotherapy, the combination of venetoclax with low-dose cytarabine (+LDAC) may be a safe and effective treatment option, inducing high rates of response and reducing mortality risk, a recent study has found.

Concomitant administration of the human epidermal growth factor receptor 2 (HER2)–targeted antibody-drug conjugate trastuzumab deruxtecan (T-DXd) with the OATP1B/CYP3A inhibitor ritonavir or the strong CYP3A inhibitor itraconazole appears to be safe and does not produce a clinically meaningful change in the pharmacokinetics of T-DXd or DXd, according to a phase I study.

The application of ruxolitinib cream led to significant improvements in facial and total body repigmentation among adolescents and adults with vitiligo, according to two phase III studies presented at EADV 2021.