Prophylaxis with high-dose methotrexate suppresses isolated CNS relapse risk in DLBCL
High-dose methotrexate (HDMTX) helps prevent isolated central nervous system (CNS) relapse in patients with diffuse large B cell lymphoma (DLBCL), a recent study has found. On the other hand, HDMTX seems to have no impact on systemic CNS relapse, systemic relapse, or survival.