News & Updates

Regdanvimab for COVID-19 effective against Delta variant

13 Jan 2023

The neutralizing antibody regdanvimab appears to be useful in the treatment of mild-to-moderate COVID-19, with a recent study showing that the drug may prevent disease worsening in patients, including those infected with the Delta variant.

Regdanvimab for COVID-19 effective against Delta variant

13 Jan 2023

JAK inhibitors pose increased risk of developing shingles

12 Jan 2023

Exposure to the Janus kinase (JAK) inhibitors tofacitinib and upadacitinib, as well as to JAK inhibitors as a class, appears to put individuals at increased risk of developing herpes zoster infection, with the risk increasing at higher doses, as reported in a study.

JAK inhibitors pose increased risk of developing shingles

12 Jan 2023

Protocol-driven evaluation may improve drug allergy label accuracy

11 Jan 2023 by

A study in Singapore has found 75-percent inaccuracy in drug allergy labels among patients, indicating the importance of drug allergy evaluation in verifying these labels.

Protocol-driven evaluation may improve drug allergy label accuracy

11 Jan 2023

Meta-analysis: No link between PPI use and gastric cancer

11 Jan 2023

Proton pump inhibitor (PPI) therapy does not appear to put individuals who require gastric acid suppression at increased risk of gastric cancer, according to a study.

Meta-analysis: No link between PPI use and gastric cancer

11 Jan 2023

Cirrhosis inpatients take more opioids, fewer nonopioid analgesics than noncirrhosis patients

10 Jan 2023

Inpatients normally use analgesics for pain, with comparable rates between those with and without cirrhosis, according to a recent study. Patients with cirrhosis, especially decompensated ones, are less likely to use acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) and more likely to use opioid analgesics.

Cirrhosis inpatients take more opioids, fewer nonopioid analgesics than noncirrhosis patients

10 Jan 2023

Sodium acetate a safe, efficacious option for alkalinization in patients on high-dose MTX

10 Jan 2023 by

Intravenous (IV) sodium acetate is as efficacious and safe as IV sodium bicarbonate for urine alkalinization with high-dose methotrexate (MTX) and may be used as a substitute in case of shortage, suggests a retrospective study.

Sodium acetate a safe, efficacious option for alkalinization in patients on high-dose MTX

10 Jan 2023

Supratherapeutic infliximab levels do not predict complications risk in CD patients

10 Jan 2023

Trough levels of infliximab are not predictive of the risk of short-term infectious (IC) or noninfectious complications (NIC) in adult patients with Crohn’s disease (CD), reports a study.

Supratherapeutic infliximab levels do not predict complications risk in CD patients

10 Jan 2023

Cardiovascular death among seniors with pneumonia down with antibiotic therapy

10 Jan 2023

In the treatment of older patients hospitalized with community-acquired pneumonia, the use of guideline-concordant antibiotic therapy significantly lowers the risk of cardiovascular death in the first year of follow-up, as reported in a study.

Cardiovascular death among seniors with pneumonia down with antibiotic therapy

10 Jan 2023

Corticosteroid poses no excess mortality risk in drug-induced liver injury

09 Jan 2023

Treatment with corticosteroid in patients with drug-induced liver injury (DILI) does not appear to contribute to increased risk of death but rather helps normalize liver enzymes, as shown in a study.

Corticosteroid poses no excess mortality risk in drug-induced liver injury

09 Jan 2023

Valacyclovir after allogeneic HCT reduces CMV infection

09 Jan 2023 by

Viral prophylaxis with valacyclovir 1 g three times daily following allogeneic haematopoietic cell transplantation (HCT) results in a lower incidence of clinically significant cytomegalovirus (CMV) infection as compared with acyclovir, according to a study.

Valacyclovir after allogeneic HCT reduces CMV infection

09 Jan 2023

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Regdanvimab for COVID-19 effective against Delta variant

Regdanvimab for COVID-19 effective against Delta variant

JAK inhibitors pose increased risk of developing shingles

JAK inhibitors pose increased risk of developing shingles

Protocol-driven evaluation may improve drug allergy label accuracy

Protocol-driven evaluation may improve drug allergy label accuracy

Meta-analysis: No link between PPI use and gastric cancer

Meta-analysis: No link between PPI use and gastric cancer

Cirrhosis inpatients take more opioids, fewer nonopioid analgesics than noncirrhosis patients

Cirrhosis inpatients take more opioids, fewer nonopioid analgesics than noncirrhosis patients

Sodium acetate a safe, efficacious option for alkalinization in patients on high-dose MTX

Sodium acetate a safe, efficacious option for alkalinization in patients on high-dose MTX

Supratherapeutic infliximab levels do not predict complications risk in CD patients

Supratherapeutic infliximab levels do not predict complications risk in CD patients

Cardiovascular death among seniors with pneumonia down with antibiotic therapy

Cardiovascular death among seniors with pneumonia down with antibiotic therapy

Corticosteroid poses no excess mortality risk in drug-induced liver injury

Corticosteroid poses no excess mortality risk in drug-induced liver injury

Valacyclovir after allogeneic HCT reduces CMV infection

Valacyclovir after allogeneic HCT reduces CMV infection