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VELO supports liquid biopsy-guided anti-EGFR rechallenge therapy in mCRC
In the phase II VELO trial, third-line (3L) treatment with the anti-EGFR* monoclonal antibody (mAb) panitumumab and standard of care (SoC) improved progression-free survival (PFS) in patients with refractory RAS wild-type metastatic colorectal cancer (WT mCRC).
VELO supports liquid biopsy-guided anti-EGFR rechallenge therapy in mCRC
12 Sep 2023Better assessment of energy requirements needed in CRC patients
Using 30 kcal/kg to predict energy requirements overestimates total energy expenditure (TEE) by 1.44 times in patients with colorectal cancer (CRC) in a controlled sedentary environment, as shown in a study. In addition, TEE is outside of the predicted requirement range for most.
Better assessment of energy requirements needed in CRC patients
07 Sep 2023Anti-HER-2/neu vaccine may benefit gastric cancer patients
In patients with HER-2-overexpressing metastatic or advanced gastric/gastroesophageal (G/GEJ) adenocarcinoma, a regimen comprising standard-of-care chemotherapy and a HER2-targeting peptide vaccine induced antibody responses that corresponded with tumour size reduction, according to an analysis of the HERIZON study which looked into the correlation between antibody responses and clinical outcomes.