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Selgantolimod well tolerated, induces serologic changes in CHB
Treatment with the oral Toll-like receptor 8 (TLR8) agonist selgantolimod once weekly for 24 weeks is well tolerated and generally safe in patients with chronic hepatitis B (CHB) under viral suppression, according to a recent study.
Selgantolimod well tolerated, induces serologic changes in CHB
09 Mar 2023Gene links breast cancer to stress, circadian disruption
Two researchers from the Philippines have discovered a gene the connects breast cancer development to stress and body clock disruption. In a recent study, they have shown the mechanism behind hormone and circadian regulation of the tumour-suppressor gene, Krüppel-like factor 9 (KLF9), and its effect on breast cancer progression.
Gene links breast cancer to stress, circadian disruption
09 Mar 2023Deep-brain stimulation affords greater seizure reduction than vagus nerve stimulation
Among the neurostimulation devices used in the treatment of generalized epilepsy, deep-brain stimulation performs better than vagus nerve stimulation at reducing seizure frequency, as reported in a study. On the other hand, while results for responsive neurostimulation are promising, further research is needed.
Deep-brain stimulation affords greater seizure reduction than vagus nerve stimulation
09 Mar 2023Prenatal exposure to plastic chemicals ups asthma risk in male offspring
Prenatal exposure to plastic-derived chemicals, such as bisphenol A (BPA) and phthalates, tends to increase the risk of asthma, particularly in males, a study has shown.
Prenatal exposure to plastic chemicals ups asthma risk in male offspring
09 Mar 2023Peg lambda cuts hospitalization, ER visits in COVID-19 outpatients
Early treatment with a single dose of pegylated recombinant IL-29 type III interferon (IFN), otherwise known as peg lambda, significantly reduced clinical events in the phase III TOGETHER study evaluating mostly vaccinated, acutely symptomatic COVID-19 outpatients.
Peg lambda cuts hospitalization, ER visits in COVID-19 outpatients
09 Mar 2023COVID-19 infection in early pregnancy ups risk of stillbirth
Pregnant women who contract COVID-19 during early and mid-pregnancy are at risk of stillbirth, but this risk may not be present when infection occurs at any time during the third trimester or before delivery, as reported in a study.
COVID-19 infection in early pregnancy ups risk of stillbirth
08 Mar 2023FIB-4 changes linked to risk of cirrhosis, HCC in NAFLD
Longitudinal changes in fibrosis-4 (FIB-4) score are strongly predictive of progression to cirrhosis and hepatocellular carcinoma (HCC) in patients with nonalcoholic fatty liver disease (NAFLD), reveals a study.
FIB-4 changes linked to risk of cirrhosis, HCC in NAFLD
08 Mar 2023Mobile app captures symptoms, biometrics of bladder cancer patients after cystectomy
Patients with bladder cancer who underwent radical cystectomy may benefit from the use of smartphones and wearable technology to monitor their symptoms as well as biometric data, according to a recent study.