News &amp; Updates

Children with asthma are less likely to respond to inhaled corticosteroid (ICS) if they also happen to obese or overweight, suggests a study presented at ERS 2021.

Kids with asthma who are obese respond poorly to ICS

Sintilimab-chemo a new first-line treatment alternative for GI cancers?

Interim results of two phase III ORIENT trials presented at ESMO 2021 underscore the potential of a combination regimen comprising the PD-1 inhibitor sintilimab and chemotherapy (CT) as a first-line therapeutic alternative for gastrointestinal cancers, particularly advanced, recurrent, or metastatic oesophageal squamous cell carcinoma (SCC) and gastric/gastroesophageal junction (G/GEJ) adenocarcinoma.

Sintilimab-chemo a new first-line treatment alternative for GI cancers?

COVID-19 booster gets FDA panel backing for 65 and up; blanket use shot down

Advisers to the US FDA* unanimously voted for emergency use authorization (EUA) of the Pfizer/BioNTech COVID-19 vaccine booster dose in people 65 years and older and those at high risk of severe COVID-19.

COVID-19 booster gets FDA panel backing for 65 and up; blanket use shot down

BP target in older Chinese: How low can clinicians go?

Under 130 mm Hg – that’s how low clinicians can go in terms of systolic blood pressure (SBP) to reduce cardiovascular events in older, hypertensive Chinese patients, suggests the multicentre STEP* trial.

BP target in older Chinese: How low can clinicians go?

Inhaled budesonide may be effective for treating early COVID-19 in adults

21 Sep 2021 by

The administration of inhaled budesonide for the treatment of early COVID-19 in adults reduced the probability of needing urgent medical care and time to recovery, according to findings from the STOIC* trial presented at ERS 2021.

Inhaled budesonide may be effective for treating early COVID-19 in adults

$Oxcarbazepine tied to increased risk of fragility fracture in children$

Oxcarbazepine tied to increased risk of fragility fracture in children

In the treatment of children with epilepsy, oxcarbazepine (OXC), but not levetiracetam (LEV), appears to contribute to a higher risk of fragility fracture, a study has found.

Oxcarbazepine tied to increased risk of fragility fracture in children

Age, sex, certain drugs up risk of advanced colorectal neoplasia in CKD

The risk of developing advanced colorectal neoplasia in patients with chronic kidney disease (CKD) is strongly associated with older age, male sex, and exposure to erythropoiesis-stimulating agents and azathioprine, a study has found.

Age, sex, certain drugs up risk of advanced colorectal neoplasia in CKD

Inhaled colistimethate sodium reduces bronchiectasis exacerbations

21 Sep 2021 by

The use of colistimethate sodium (CMS), delivered via the I-neb, reduces pulmonary exacerbations among patients with bronchiectasis and chronic Pseudomonas aeruginosa (P. aeruginosa) infection, according to the PROMIS-1* study presented at ERS 2021.

Inhaled colistimethate sodium reduces bronchiectasis exacerbations