News & Updates

$New drug casts hope for patients with refractory acute leukaemias$

New drug casts hope for patients with refractory acute leukaemias

19 May 2023 by

Revumenib, a novel potent, selective oral inhibitor of the menin-KMT2A interaction, demonstrated promising antileukaemic activity in children and adults with highly refractory acute leukaemia with KMT2Ar* or NPM1* mutation, a phase I dose-escalation study finds.

New drug casts hope for patients with refractory acute leukaemias

19 May 2023

Nirsevimab safe, effective against RSV lower respiratory tract infection

18 May 2023 by

A single dose of nirsevimab administered before or during the respiratory syncytial virus (RSV) season provides protection against RSV lower respiratory tract infection (LRTI) hospitalization and very severe infection in infants, according to the preliminary results of a clinical trial conducted in real-world settings.

Nirsevimab safe, effective against RSV lower respiratory tract infection

18 May 2023

CBD yields comparable benefits in kids, adults with Lennox-Gastaut and Dravet syndrome

17 May 2023 by

Children with Lennox-Gastaut syndrome (LGS) and Dravet's syndrome (DS) achieve improvements in both seizure management and nonseizure outcomes following treatment with cannabidiol (CBD)—a success echoed in their adult counterparts, as shown in a study presented at AAN 2023.

CBD yields comparable benefits in kids, adults with Lennox-Gastaut and Dravet syndrome

17 May 2023

Large for gestational age tied to higher cardiometabolic risks

17 May 2023

Individuals born large for gestational age (LGA) are more likely to develop obesity and metabolic syndrome later in life than those born appropriate for gestational age, suggests a study.

Large for gestational age tied to higher cardiometabolic risks

17 May 2023

Dengue vaccine provides ample protection to children

17 May 2023 by

The dengue vaccine confers substantial protective benefit on children aged 10 to 15 years, reports a study in the Philippines, which was presented at the recent ESPID 2023.

Dengue vaccine provides ample protection to children

17 May 2023

Ataluren improves ambulation in nonsense mutation DMD

16 May 2023 by

Treatment with ataluren improves ambulatory function, as assessed by the 6-minute walk distance (6MWD) test, among boys with nonsense mutation Duchenne muscular dystrophy (nmDMD), according to the subgroup analysis of Study 041 trial presented at AAN 2023.

Ataluren improves ambulation in nonsense mutation DMD

16 May 2023

Original New Drug Application Approvals by US FDA (01-15 May 2023)

16 May 2023

New drug applications approved by US FDA as of 01-15 May 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01-15 May 2023)

16 May 2023

Self-compassion, relation satisfaction mediate child sexual abuse-sexual functioning link

14 May 2023

Self-compassion and relationship satisfaction play a significant role in the relationship between sexual functioning and child sexual abuse (CSA), a study has found.

Self-compassion, relation satisfaction mediate child sexual abuse-sexual functioning link

14 May 2023

Should parenteral nutrition start at a lower birth weight threshold?

11 May 2023

A recent single-centre study, which reduced the birth weight (BW) threshold for bridging parenteral nutrition (PN) from 1,500 to 1,250 g, has found that PN was initiated in about one in four infants with a BW between 1,250 and 1,500 g.

Should parenteral nutrition start at a lower birth weight threshold?

11 May 2023

Prior carbapenem use ups S. maltophilia bloodstream infection in children

09 May 2023

Children with prior use of carbapenem are at increased risk of developing Stenotrophomonas maltophilia bloodstream infection (BSI), suggests a study. In addition, admission to the paediatric intensive care unit (PICU) due to BSI and prior glycopeptide use are significantly associated with the mortality rate in patients with S. maltophilia BSIs

Prior carbapenem use ups S. maltophilia bloodstream infection in children

09 May 2023

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New drug casts hope for patients with refractory acute leukaemias

New drug casts hope for patients with refractory acute leukaemias

Nirsevimab safe, effective against RSV lower respiratory tract infection

Nirsevimab safe, effective against RSV lower respiratory tract infection

CBD yields comparable benefits in kids, adults with Lennox-Gastaut and Dravet syndrome

CBD yields comparable benefits in kids, adults with Lennox-Gastaut and Dravet syndrome

Large for gestational age tied to higher cardiometabolic risks

Large for gestational age tied to higher cardiometabolic risks

Dengue vaccine provides ample protection to children

Dengue vaccine provides ample protection to children

Ataluren improves ambulation in nonsense mutation DMD

Ataluren improves ambulation in nonsense mutation DMD

Original New Drug Application Approvals by US FDA (01-15 May 2023)

Original New Drug Application Approvals by US FDA (01-15 May 2023)

Self-compassion, relation satisfaction mediate child sexual abuse-sexual functioning link

Self-compassion, relation satisfaction mediate child sexual abuse-sexual functioning link

Should parenteral nutrition start at a lower birth weight threshold?

Should parenteral nutrition start at a lower birth weight threshold?

Prior carbapenem use ups S. maltophilia bloodstream infection in children

Prior carbapenem use ups S. maltophilia bloodstream infection in children