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Arginine depletion plus chemo ups survival in rare lung cancer
In the pivotal phase II/III ATOMIC-Meso* trial, adding the first-in-class, arginine-depleting agent pegargiminase to standard first-line platinum-pemetrexed chemotherapy prolongs overall survival (OS) and progression-free survival (PFS) in patients with treatment-naïve, nonresectable, nonepithelioid pleural mesothelioma.
Arginine depletion plus chemo ups survival in rare lung cancer
13 Sep 2024
Trial of two tenofovir-containing regimens for HIV/HBV co-infection: Insights from ALLIANCE
The triplet combination of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is as good as dolutegravir + emtricitabine/tenofovir disoproxil fumarate (DTG+F/TDF) in terms of efficacy for HIV control but results in better hepatitis B virus (HBV) outcomes in patients with HIV/HBV co-infection, according to results of the phase III ALLIANCE trial presented at IAS 2022.
Trial of two tenofovir-containing regimens for HIV/HBV co-infection: Insights from ALLIANCE
11 Sep 2024
COVID-19 infection ups CV risk in people living with HIV
People living with HIV (PLWH) who were diagnosed with COVID-19 had a 35-percent higher risk of a major cardiovascular (CV) event in the following year than PLWH without COVID in a Spanish study.
COVID-19 infection ups CV risk in people living with HIV
26 Aug 2024![[MK TEST DO NOT TOUCH] Deuruxolitinib helps restore crowning glory in alopecia areata](https://sitmspst.blob.core.windows.net/images/articles/thriveaa1-and-thrive-aa2-87e6d5ec-94c6-405b-a380-d331c4dcc5fc-square.jpg)
[MK TEST DO NOT TOUCH] Deuruxolitinib helps restore crowning glory in alopecia areata
Pooled analyses of the phase III THRIVEAA1 and THRIVE-AA2 trials underpin the potential of the selective oral JAK* 1/2 inhibitor deuruxolitinib to effectively and safely reverse hair loss in adults with moderate-to-severe alopecia areata (AA).