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Empagliflozin: A new dawn for heart failure treatment across the ejection fraction spectrum
Initially approved to improve glycaemic control and reduce cardiovascular death in adults with type 2 diabetes (T2D), the SGLT-2* inhibitor empagliflozin reduced hospitalization for heart failure (HFH) or cardiovascular death and delayed renal function decline when added to recommended therapy in patients with heart failure and reduced ejection fraction (HFrEF) in the EMPEROR-Reduced** trial. The EMPEROR-Preserved** trial has now shown that the benefits of empagliflozin extend to patients with heart failure and preserved ejection fraction (HFpEF).
Empagliflozin: A new dawn for heart failure treatment across the ejection fraction spectrum
06 Jun 2022Iatrogenic tumour seeding not a risk factor for metachronous CRC
In patients with colorectal cancer (CRC), biopsy of nontumour sites after biopsy of the primary cancer is unlikely to cause metachronous cancers, a study reports.
Iatrogenic tumour seeding not a risk factor for metachronous CRC
06 Jun 2022Vision impairment linked to depression, anxiety among kids
Children with vision impairment often experience greater symptoms of depression and anxiety, according to a recent study. Surgical treatment helps improve these mental health symptoms.
Vision impairment linked to depression, anxiety among kids
06 Jun 2022Elacestrant ups PFS vs SoC ET in ER-positive, HER2-negative advanced breast cancer
Elacestrant, a novel oral selective oestrogen receptor (ER) degrader, significantly improves progression-free survival (PFS) vs standard-of-care (SoC) endocrine therapy (ET) in patients with ER-positive, HER2-negative advanced breast cancer whose disease progressed after 1–2 prior lines of ET and a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, results of the phase III EMERALD trial have shown.
Elacestrant ups PFS vs SoC ET in ER-positive, HER2-negative advanced breast cancer
06 Jun 2022NAFLD tied to CVD risk even in lean patients
Individuals with nonalcoholic fatty liver disease (NAFLD) – despite having a lean body or healthy BMI – are at an elevated risk for peripheral vascular disease, stroke, and cardiovascular disease (CVD), a finding that surprises gastroenterologists and researchers at DDW 2022.