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Antiretroviral therapy with INSTI maintains low switch rates among people with HIV
Persons living with HIV (PLWH) often switch from first-line antiretroviral therapies (ART) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) or protease inhibitors (PI) to second-line integrase strand transfer inhibitors (INSTI), a recent Japan study has found. PLWHs tend to stay on INSTIs for a long time thereafter.
Antiretroviral therapy with INSTI maintains low switch rates among people with HIV
13 Feb 2022
Risk downgrade common in GGG3 prostate cancer patients with single positive biopsy core
In Gleason grade group (GGG) 3 prostate cancer patients with a single intermediate-risk positive biopsy core, risk downgrading appears to be more likely than upgrading, reports a new study.
Risk downgrade common in GGG3 prostate cancer patients with single positive biopsy core
13 Feb 2022
Recurrent node-positive breast cancer reveals distant metastasis in patients
Distant metastasis is present in all patients with node-positive breast cancer (NPBC) at the time of recurrence, reveals a study. Compared with diffusely metastatic (DM) patients, those with oligometastasis (OM) have shorter time to recurrence but longer overall survival (OS).