News & Updates

Switching to a fulvestrant-palbociclib regimen prior to disease progression after detection of elevated ESR1 mutations in the blood of patients with hormone receptor-positive (HR+), HER2-negative (HER2-) metastatic breast cancer (mBC) who were receiving aromatase inhibitors (AIs) plus palbociclib extended their progression-free survival (PFS), results of the phase III PADA-1 trial showed.

A recent study has shown that more than a quarter of young adults are seropositive for SARS-CoV-2, many of whom show single positivity with IgM. Such seropositivity was higher among those who had cases of the coronavirus disease 2019 (COVID-19) in the household and those who used public transport.

Autoimmune hepatitis (AIH), a chronic inflammatory liver disease, appears to increase the 10-year risk of cancer by 1.5-fold relative to age- and sex-matched controls, a study has shown.

Antihypertensive therapy (AHT) may be used safely during the COVID-19 pandemic, as no evidence suggest that it can increase the risk of SARS-CoV-2 infection or death, according to a UK study. In addition, most classes of antihypertensives are negatively associated with COVID-19 diagnosis.

The 3-dimensional (3D) deep learning-based automated digital gonioscopy system (DGS) effectively identifies eyes with suspected primary angle-closure glaucoma (PACG), demonstrating its potential for wide use in the primary eye care community for screening of patients at high risk of developing PACG, suggests a study.

The benefits of the 5:2 diet – which involves limited caloric intake (500–600 kcal) for 2 nonconsecutive days per week only – mirrored those achieved with a multicomponent weight management advice, according to a UK study on adults with obesity. However, the benefits eventually waned, even when intensified with group support.

Adding duloxetine to usual care does not appear to produce significant relief from chronic osteoarthritis pain as compared with usual care alone, a study has found.