News &amp; Updates

Treating myeloproliferative neoplasm patients with direct oral anticoagulants (DOACs) may induce higher risks of bleeding events, with no particular spikes in thrombosis rates, a recent study has found.

DOACs up bleeding risk in patients with myeloproliferative neoplasms

CKD incidence varies widely among Singapore’s ethnic groups

29 Dec 2021 by

Chronic kidney disease (CKD) is common among Asians, particularly in the main ethnic groups in Singapore, with incidence rates ranging between 6 percent and 10 percent, according to a recent study. Such ethnicity-dependent disparities could be partially explained by clinical and socioeconomic factors that may be valuable as targets for intervention.

CKD incidence varies widely among Singapore’s ethnic groups

Post-diagnosis use of risk stratification tools improves assessment of SMM patients

Despite only being validated for use at diagnosis, risk stratification scores, such as the Mayo-2018 and the International Myeloma Working Group (IMWG)-2020 criteria, appear to be viable for post-diagnosis use in patients with smouldering multiple myeloma (SMM), a recent study has found.

Post-diagnosis use of risk stratification tools improves assessment of SMM patients

29 Dec 2021

Changes in MetS diagnosis affects psoriasis risk

The risk of psoriasis is elevated in patients with continuous metabolic syndrome (MetS) and in those with newly developed MetS, a recent study has found. In contrast, such risk is absent in individuals with only a history of MetS.

Changes in MetS diagnosis affects psoriasis risk

28 Dec 2021

Ovarian suppression + AI prevents recurrence in premenopausal breast cancer over long term

The benefits in terms of prolonged disease-free survival (DFS) and reduced risk of recurrence with ovarian function suppression (OFS) persisted over 12–13 years in premenopausal women with hormone receptor-positive (HR+) breast cancer, according to new data from the TEXT and SOFT randomized trials presented at SABCS 2021.

Ovarian suppression + AI prevents recurrence in premenopausal breast cancer over long term

No clear evidence linking foods to natural menopause onset

Eating green and yellow vegetables in high amounts or a keeping vegetarian diet in general is associated with an earlier onset of natural menopause, whereas a low intake of alcohol and a high intake of some dairy products are linked to a later onset, according to the results of a meta-analysis. However, the associations have been inconsistent, and the findings overall are not replicated among the studies included.

No clear evidence linking foods to natural menopause onset

Depression prevalent in children, adults with hidradenitis suppurativa

Depression is not uncommon among children, adolescents, and adults with hidradenitis suppurativa (HS), reports a study, adding that periodic screening for depression may be necessary.

Depression prevalent in children, adults with hidradenitis suppurativa

28 Dec 2021

Omicron raises new fears

The threat of Omicron is real, with scientists working at breakneck speed to better understand its virulence and potential ability to evade currently approved vaccines.

Omicron raises new fears

Chronic wounds compromise health-related quality of life

Chronic wounds, particularly arterial ulcers, severely impair patients’ health-related quality of life by restricting their mobility and self-care, and by causing pain, discomfort, anxiety, and depression, according to a recent Singapore study.

Chronic wounds compromise health-related quality of life

COMMODORE trial steers gilteritinib to the fore of AML treatment

Gilteritinib provided significant survival benefit and demonstrated a favourable safety and tolerability profile in Asian patients with relapsed/refractory FLT3-mutated acute myeloid leukaemia (R/R FLT3mut+ AML) compared with salvage chemotherapy (SC), findings from the phase III COMMODORE trial suggest.

COMMODORE trial steers gilteritinib to the fore of AML treatment