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COSMIC-313 highlights benefit of triplet regimen in RCC
In the COSMIC-313 trial, the addition of the tyrosine kinase inhibitor (TKI) cabozantinib to the immune checkpoint inhibitor (ICI)-doublet regimen comprising nivolumab and ipilimumab (NIVO/IPI) improved progression-free survival (PFS) in patients with previously untreated, advanced renal-cell carcinoma (RCC) who had intermediate or poor prognostic risk according to the IMDC* category.
COSMIC-313 highlights benefit of triplet regimen in RCC
15 Sep 2023Is it safe to take olmesartan in combination therapy for advanced hypertension?
Use of olmesartan in combination practice is safe and results in similar cardiovascular composite outcomes, including myocardial infarction (MI), when compared with active comparators in hypertensive patients who need more than two antihypertensive medications, reports a study.
Is it safe to take olmesartan in combination therapy for advanced hypertension?
14 Sep 2023Bulevirtide boasts high barrier to resistance for chronic hepatitis delta
A recent study has found no amino acid substitutions associated with reduced sensitivity to bulevirtide (BLV) monotherapy, a hepatitis D/B virus (HDV/HBV) entry inhibitor, at baseline or week 24 in patients with virologic breakthrough after BLV treatment.