News &amp; Updates

An analysis of three randomized controlled trials (RCTs) has shown the efficacy and safety of berdazimer gel, a topical, antiviral, nitric oxide-releasing medication, in the treatment of molluscum contagiosum (MC) lesions in patients aged 6 months and older. Application-site pain and erythema are the most common adverse events (AEs) related to treatment.

Berdazimer gel reduces molluscum contagiosum lesions in children

22 Jan 2024

Is night-time better than morning dosing of antihypertensives?

Bedtime dosing of antihypertensive medication is neither better nor worse than morning dosing when it comes to the subsequent risk of all-cause or cardiovascular mortality, according to a study.

Is night-time better than morning dosing of antihypertensives?

22 Jan 2024

The 100,000 Genomes Project: Insights from the cancer programme

Recently published data from the cancer programme of the 100,000 Genomes Project, which maps out the genomic patterns of patients with different cancer types using whole-genome sequencing (WGS), have provided insights on integrating genomics into routine cancer care.

The 100,000 Genomes Project: Insights from the cancer programme

Cancer survivors may benefit from social media-based interventions

A meta-analysis and meta-regression of randomized controlled trials (RCTs) found that social media-based interventions – which are interventions from any form of online medium that enables participant interaction (eg, Facebook, Instagram, TikTok, Twitter) – may be beneficial for cancer patients.

Cancer survivors may benefit from social media-based interventions

Treating type 2 diabetes mellitus with G.R.A.C.E.

A challenging aspect of glycaemic control presents in patients diagnosed with early-onset type 2 diabetes mellitus (T2DM). Considering this challenge, how can effective management of glycaemic control be achieved in patients with uncontrolled T2DM who are hesitant to incorporate multiple oral antidiabetic drugs into their current regimen? In this case study, Dr Matthew Tan shared his clinical experience in managing a young adult patient with T2DM using GLYXAMBI^®, a fixed-dose combination of empagliflozin and linagliptin taken once daily. He demonstrated how applying the G.R.A.C.E. concept to the treatment improved the patient’s clinical outcome.

This advertorial is sponsored as an educational programme by Boehringer Ingelheim Singapore Pte. Ltd.

Treating type 2 diabetes mellitus with G.R.A.C.E.

Effectiveness of mRNA Vaccines Against Omicron XBB Infection in Singaporean Children Under 5: A Population-Based Cohort Study

Limited data exists on COVID-19 mRNA vaccine effectiveness in children aged 1–4 years, particularly against Omicron subvariants. In a cohort study conducted during Omicron XBB subvariant predominant period in Singapore, completing the primary COVID-19 mRNA vaccine series significantly protected against COVID-19 infection in this age group, with 45.2% and 63.3% vaccine effectiveness in partially and fully vaccinated children, respectively. Vaccine effectiveness was also robust at 74.6% in children with prior COVID-19 infection who received at least one vaccine dose.

Effectiveness of mRNA Vaccines Against Omicron XBB Infection in Singaporean Children Under 5: A Population-Based Cohort Study

Capivasertib fits the bill for HR+, HER2– ABC

Capivasertib, when added to fulvestrant, prolonged progression-free survival (PFS) by 4.1 months in an analysis of Chinese patients with hormone receptor–positive (HR+), HER2-negative (HER2– ABC) advanced breast cancer (ABC) whose disease had progressed on aromatase inhibitor, with or without a cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor in the phase III CAPItello-291 trial.

Capivasertib fits the bill for HR+, HER2– ABC

22 Jan 2024

Teen study: The more the siblings, the poorer the mental health

21 Jan 2024 by

For teens, growing up in large families can take a toll on their mental health.

Teen study: The more the siblings, the poorer the mental health

High systolic BPV tied to greater frailty risk in older adults

An elevated systolic blood pressure (BP) variability (BPV) in healthy older adults may lead to a higher risk of frailty regardless of their mean BP, suggests a study.

High systolic BPV tied to greater frailty risk in older adults

Cancer diagnosis in children ups risk of parental suicide attempt

21 Jan 2024 by

The risk of suicide attempts among parents of children with cancer is higher during the first years following cancer diagnosis, particularly when the child is diagnosed at age 18 years or below, or with an aggressive or fatal form of cancer, a study has found.

Cancer diagnosis in children ups risk of parental suicide attempt