News & Updates

PRECONNECT final analysis underline potential of trifluridine/tipiracil for metastatic CRC

03 Sep 2021 by

In the final analysis of the phase IIIb PRECONNECT study presented at ESMO GI 2021, a chemotherapeutic regimen comprising trifluridine/tipiracil (FTD/TPI) continued to show favourable efficacy and safety for individuals with previously treated metastatic colorectal cancer (mCRC), with no new safety concerns.

PRECONNECT final analysis underline potential of trifluridine/tipiracil for metastatic CRC

03 Sep 2021

Ramucirumab + paclitaxel extends survival in gastric cancer, regardless of liver metastasis

02 Sep 2021 by

Adding the VEGFR*-2 antagonist ramucirumab to paclitaxel extends survival of patients with advanced gastric/GEJ** adenocarcinoma compared with paclitaxel alone, regardless of liver metastasis status, according to a post hoc analysis of the RAINBOW*** trial presented at the ESMO GI 2021 Congress.

Ramucirumab + paclitaxel extends survival in gastric cancer, regardless of liver metastasis

02 Sep 2021

Chemo dose may affect survival in obese CRC patients

01 Sep 2021 by

Obese patients with colorectal cancer (CRC) may be receiving lower cumulative doses of chemotherapy than non-obese patients which may impact their survival outcomes, according to results of a study from the OCTOPUS consortium.

Chemo dose may affect survival in obese CRC patients

01 Sep 2021

Pembrolizumab-trastuzumab-chemo a new treatment alternative for gastric cancer?

01 Sep 2021 by

In a prespecified interim analysis of the phase III KEYNOTE-811 study presented at ESMO GI 2021, the addition of pembrolizumab to standard of care (SoC) first-line therapy comprising trastuzumab and chemotherapy led to a significant improvement in overall response rate (ORR) in previously untreated individuals with HER2-positive, metastatic gastric or gastroesophageal junction (G/GEJ) cancer.

Pembrolizumab-trastuzumab-chemo a new treatment alternative for gastric cancer?

01 Sep 2021

Corticosteroid use before embryo transfer improves ART success in women with RA, IBD

31 Aug 2021

Among women with rheumatoid arthritis (RA) and/or inflammatory bowel disease (IBD) undergoing assisted reproductive technology (ART) procedures, embryo transfer at the blastocyst stage and corticosteroid use prior to ART appear to improve chances of a live birth, a study has found.

Corticosteroid use before embryo transfer improves ART success in women with RA, IBD

31 Aug 2021

Incomplete resection predicts recurrence of colorectal neoplastic polyps

30 Aug 2021

Incomplete resection of colon segments is significantly associated with a higher risk for future neoplasia and advanced neoplasia than those with complete resection, a study has found.

Incomplete resection predicts recurrence of colorectal neoplastic polyps

30 Aug 2021

Gut microbiome, composition tied to hypertension risk in women

26 Aug 2021 by

Gut microbiome diversity and composition appear to contribute to the development of hypertension in women, suggest the results of a study.

Gut microbiome, composition tied to hypertension risk in women

26 Aug 2021

PPI use may increase death risk in COVID-19 patients

24 Aug 2021

Users of proton pump inhibitor (PPI) who tested negative for COVID-19 show higher salivary angiotensin-converting enzyme 2 (ACE2) expression, reports a study. In addition, PPI use seems to heighten the risk of death in COVID-19 patients, particularly African Americans.

PPI use may increase death risk in COVID-19 patients

24 Aug 2021

Long-term ranitidine use ups bladder cancer risk

23 Aug 2021

Use of ranitidine in the long term appears to increase the risk of bladder cancer, reveals a large population-based study.

Long-term ranitidine use ups bladder cancer risk

23 Aug 2021

Universal DAA access tied to reduced HCV prevalence in PLHIV

20 Aug 2021 by

Universal access to direct-acting antivirals (DAAs) may have led to the low prevalence of hepatitis C viraemia among people living with HIV (PLHIV) in The Netherlands, according to a study presented at IAS 2021.

Universal DAA access tied to reduced HCV prevalence in PLHIV

20 Aug 2021

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PRECONNECT final analysis underline potential of trifluridine/tipiracil for metastatic CRC

PRECONNECT final analysis underline potential of trifluridine/tipiracil for metastatic CRC

Ramucirumab + paclitaxel extends survival in gastric cancer, regardless of liver metastasis

Ramucirumab + paclitaxel extends survival in gastric cancer, regardless of liver metastasis

Chemo dose may affect survival in obese CRC patients

Chemo dose may affect survival in obese CRC patients

Pembrolizumab-trastuzumab-chemo a new treatment alternative for gastric cancer?

Pembrolizumab-trastuzumab-chemo a new treatment alternative for gastric cancer?

Corticosteroid use before embryo transfer improves ART success in women with RA, IBD

Corticosteroid use before embryo transfer improves ART success in women with RA, IBD

Incomplete resection predicts recurrence of colorectal neoplastic polyps

Incomplete resection predicts recurrence of colorectal neoplastic polyps

Gut microbiome, composition tied to hypertension risk in women

Gut microbiome, composition tied to hypertension risk in women

PPI use may increase death risk in COVID-19 patients

PPI use may increase death risk in COVID-19 patients

Long-term ranitidine use ups bladder cancer risk

Long-term ranitidine use ups bladder cancer risk

Universal DAA access tied to reduced HCV prevalence in PLHIV

Universal DAA access tied to reduced HCV prevalence in PLHIV