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Original New Drug Application Approvals by US FDA (16 - 31 May 2022

31 May 2022

New drug applications approved by US FDA as of 16-31 May 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16 - 31 May 2022

31 May 2022

Shift work worsens MI reperfusion injury

30 May 2022

A recent study provides further proof that disruption of circadian rhythms by shift work leads to a higher risk of reperfusion injury in myocardial infarction (MI).

Shift work worsens MI reperfusion injury

30 May 2022

Acid reflux drug fails to show benefit in pre-eclampsia treatment

29 May 2022

Omeprazole falls short of improving the maternal circulating profile of sFlt-1 (soluble Fms-like tyrosine kinase-1), PlGF (placental growth factor), and ET-1 (endothelin-1) in women with established pre-eclampsia, as shown in a study.

Acid reflux drug fails to show benefit in pre-eclampsia treatment

29 May 2022

Polypill cuts risk of cardiovascular disease but not mortality

28 May 2022

Use of a fixed-dose combination therapy or a polypill effectively lowers cardiovascular risk factors but falls short of producing significant reductions in mortality, according to a systematic review and meta-analysis.

Polypill cuts risk of cardiovascular disease but not mortality

28 May 2022

Diabetics bear no extra heart burden after intense exercise

28 May 2022

High-intensity exercise induces comparable cardiac responses in type 2 diabetes (T2D) patients vs healthy individuals, a recent study has found.

Diabetics bear no extra heart burden after intense exercise

28 May 2022

Smoking cessation benefit on ASCVD as effective as 3 meds?

27 May 2022 bởi

Patients with atherosclerotic cardiovascular disease (ASCVD) who quit smoking after acute coronary syndrome or revascularization have a comparable gain in event-free years as those who are on maximal pharmaceutical treatment, according to a study presented at the ESC Preventive Cardiology 2022 annual congress.

Smoking cessation benefit on ASCVD as effective as 3 meds?

27 May 2022

Atrial fibrillation hurts survival in patients with acute pulmonary embolism

27 May 2022

About one in eight patients with acute pulmonary embolism (aPE) has atrial fibrillation (AF), which contributes to increased short- and long-term mortality, a study has found.

Atrial fibrillation hurts survival in patients with acute pulmonary embolism

27 May 2022

Tea intake may cut abdominal aortic aneurysm risk

27 May 2022 bởi

In two population-based Swedish cohorts of men and women with generally low tea consumption, tea intake was inversely associated with the incidence of abdominal aortic aneurysm (AAA).

Tea intake may cut abdominal aortic aneurysm risk

27 May 2022

Early treatment of ATTR-CM with tafamidis increases survival

27 May 2022 bởi

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive and life-threatening rare disease caused by unstable transthyretin proteins that misfold and aggregate into insoluble amyloid fibrils that deposit in the heart and other organs of the body. Tafamidis, a transthyretin stabilizer, is the first disease-modifying therapy approved for ATTR-CM. Clinical Assistant Professor Khoo Chun Yuan, Consultant Cardiologist at the National Heart Centre Singapore, discusses the importance of early diagnosis and treatment of ATTR-CM patients.

Early treatment of ATTR-CM with tafamidis increases survival

27 May 2022

Beetroot juice of no benefit to blood pressure, endothelial function

26 May 2022

Beetroot juice does not seem to be effective at lowering blood pressure or improving microvascular endothelial function in both young and old people, a recent study has found.

Beetroot juice of no benefit to blood pressure, endothelial function

26 May 2022

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Original New Drug Application Approvals by US FDA (16 - 31 May 2022

Original New Drug Application Approvals by US FDA (16 - 31 May 2022

Shift work worsens MI reperfusion injury

Shift work worsens MI reperfusion injury

Acid reflux drug fails to show benefit in pre-eclampsia treatment

Acid reflux drug fails to show benefit in pre-eclampsia treatment

Polypill cuts risk of cardiovascular disease but not mortality

Polypill cuts risk of cardiovascular disease but not mortality

Diabetics bear no extra heart burden after intense exercise

Diabetics bear no extra heart burden after intense exercise

Smoking cessation benefit on ASCVD as effective as 3 meds?

Smoking cessation benefit on ASCVD as effective as 3 meds?

Atrial fibrillation hurts survival in patients with acute pulmonary embolism

Atrial fibrillation hurts survival in patients with acute pulmonary embolism

Tea intake may cut abdominal aortic aneurysm risk

Tea intake may cut abdominal aortic aneurysm risk

Early treatment of ATTR-CM with tafamidis increases survival

Early treatment of ATTR-CM with tafamidis increases survival

Beetroot juice of no benefit to blood pressure, endothelial function

Beetroot juice of no benefit to blood pressure, endothelial function