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Original New Drug Application Approvals by US FDA (16-31 October 2024)

07 Nov 2024

New drug applications approved by US FDA as of 16-31 October 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 October 2024)

07 Nov 2024

Increased risk of inflammatory CNS diseases following anti-TNF therapy for autoimmune diseases

06 Nov 2024 by

Compared with conventional therapies, exposure to tumour necrosis factor (TNF) inhibitors is associated with increased risk of inflammatory central nervous system (CNS) diseases, irrespective of background autoimmune disease or TNF inhibitor type, a recent meta-analysis has found.

Increased risk of inflammatory CNS diseases following anti-TNF therapy for autoimmune diseases

06 Nov 2024

Opioid does little to ease pain in aSAH-related headache

04 Nov 2024

Use of opioids results in small reductions in pain among adult patients with an aneurysmal subarachnoid haemorrhage (aSAH)-related headache, and higher doses do not appear to significantly boost its efficacy in relieving pain, according to a study.

Opioid does little to ease pain in aSAH-related headache

04 Nov 2024

Pregabalin relieves pain, itch in recessive dystrophic epidermolysis bullosa

03 Nov 2024

In patients with recessive dystrophic epidermolysis bullosa, treatment with pregabalin appears to substantially reduce pain and itch, according to a randomized crossover trial.

Pregabalin relieves pain, itch in recessive dystrophic epidermolysis bullosa

03 Nov 2024

Low-field MRI for HK’s first one-stop acute stroke management model

02 Nov 2024 by

Low-field 0.23T MRI technology has been introduced recently as part of the launch of Hong Kong’s first one-stop acute stroke management model, the Emergency Stroke Unit (ESU), at Prince of Wales Hospital (PWH).

Low-field MRI for HK’s first one-stop acute stroke management model

02 Nov 2024

Lacosamide safe, efficacious for long-term seizure control in idiopathic generalized epilepsy

31 Oct 2024

In patients with idiopathic generalized epilepsy, adjunctive lacosamide treatment in the long term may safely reduce the frequency of generalized onset tonic–clonic seizures (GTCS), as shown in the open-label extension EP0012 trial.

Lacosamide safe, efficacious for long-term seizure control in idiopathic generalized epilepsy

31 Oct 2024

Hearing loss a red flag for Parkinson’s disease

29 Oct 2024

Hearing loss appears to raise the risk of later development of Parkinson’s disease (PD), and this risk may be attenuated by hearing aid use, according to a study.

Hearing loss a red flag for Parkinson’s disease

29 Oct 2024

No-sugar coffee may protect against Alzheimer’s, Parkinson’s diseases

25 Oct 2024

People who always drink coffee, particularly without sugar added, are less likely to develop Alzheimer’s disease and related dementias (ADRD) or Parkinson’s disease (PD), suggests a study.

No-sugar coffee may protect against Alzheimer’s, Parkinson’s diseases

25 Oct 2024

Dental care access suboptimal in kids with cerebral palsy, SG study shows

25 Oct 2024 by

In Singapore, children with cerebral palsy (CP) have suboptimal access to dental care, especially among those younger than 6 years, a study has shown.

Dental care access suboptimal in kids with cerebral palsy, SG study shows

25 Oct 2024

Nicardipine implants may improve aSAH outcomes

23 Oct 2024

Placing nicardipine-release implants during microsurgical aneurysm repair helps prevent angiographic vasospasm following aneurysmal subarachnoid haemorrhage (aSAH), according to a study.

Nicardipine implants may improve aSAH outcomes

23 Oct 2024

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Original New Drug Application Approvals by US FDA (16-31 October 2024)

Original New Drug Application Approvals by US FDA (16-31 October 2024)

Increased risk of inflammatory CNS diseases following anti-TNF therapy for autoimmune diseases

Increased risk of inflammatory CNS diseases following anti-TNF therapy for autoimmune diseases

Opioid does little to ease pain in aSAH-related headache

Opioid does little to ease pain in aSAH-related headache

Pregabalin relieves pain, itch in recessive dystrophic epidermolysis bullosa

Pregabalin relieves pain, itch in recessive dystrophic epidermolysis bullosa

Low-field MRI for HK’s first one-stop acute stroke management model

Low-field MRI for HK’s first one-stop acute stroke management model

Lacosamide safe, efficacious for long-term seizure control in idiopathic generalized epilepsy

Lacosamide safe, efficacious for long-term seizure control in idiopathic generalized epilepsy

Hearing loss a red flag for Parkinson’s disease

Hearing loss a red flag for Parkinson’s disease

No-sugar coffee may protect against Alzheimer’s, Parkinson’s diseases

No-sugar coffee may protect against Alzheimer’s, Parkinson’s diseases

Dental care access suboptimal in kids with cerebral palsy, SG study shows

Dental care access suboptimal in kids with cerebral palsy, SG study shows

Nicardipine implants may improve aSAH outcomes

Nicardipine implants may improve aSAH outcomes