News & Updates

Antipsychotics, antidepressants, and benzodiazepines do not appear to have a protective association with all-cause mortality in patients with schizophrenia when controlling for immortal time bias (ITB), suggesting that the effects of these drugs on mortality may be overestimated in analyses not adjusting for ITB, according to a study.

Tranexamic acid was as effective as norethisterone in reducing menstrual blood loss and the duration of menstrual period in women with heavy menstrual bleeding (HMB), according to a study presented at RCOG 2024.

In a first-of-a-kind meta-analysis comparing the efficacy and safety of different treatment options for obesity, weight loss surgery using the Roux-en-Y gastric bypass (RYGB) yields optimal weight loss than other surgical procedures or weight loss medications.

Data presented at RCOG 2024 reflect the suitability of methoxyflurane – a short-acting analgesic delivered via a handheld, self-administered inhaler device – for use in the performance of minor gynaecology procedures.

Adding intrauterine misoprostol to oxytocin significantly reduced the incidence of postpartum haemorrhage (PPH) in women who underwent caesarean section (CS) compared with oxytocin alone, according to a study presented at RCOG 2024.

In the management of preterm premature rupture of membranes (PPROM), a combination therapy of fosfomycin, clindamycin, and metronidazole has shown superiority over erythromycin plus metronidazole, while azithromycin has emerged as a promising alternative to erythromycin, with both regimens associated with favourable outcomes, as shown in two studies presented at RCOG 2024.

Evidence from a large population-based study shows no consistent association between an increased risk of cancer and exposure to antihypertensive drugs.

Treatment with high-dose VE303, a defined bacterial consortium composed of eight strains of commensal Clostridia, was associated with a significant reduction in antibiotic resistance genes (ARGs) among individuals with Clostridioides difficile infection (CDI), according to the phase II CONSORTIUM* study presented at IDWeek 2024.