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Fuzuloparib ± apatinib improves PFS in BRCA-mutated metastatic breast cancer

18 Oct 2024 by

Treatment with fuzuloparib, with or without apatinib, significantly improved progression-free survival (PFS) in patients with HER2– metastatic breast cancer (mBC) harbouring germline BRCA1/2 (gBRCA1/2) mutations compared with standard chemotherapy, according to results of a phase III study presented at ESMO 2024.

Fuzuloparib ± apatinib improves PFS in BRCA-mutated metastatic breast cancer

18 Oct 2024

Group intervention may prevent maternal obesity transmission

17 Oct 2024

A group prenatal care intervention appears beneficial in addressing several factors associated with intergenerational transmission of obesity, suggests a study in American Samoa.

Group intervention may prevent maternal obesity transmission

17 Oct 2024

Exercise may cut breast cancer risk

16 Oct 2024 by

A study conducted among Vietnamese women found that engaging in regular exercise leads to a reduction in the overall risk of breast cancer, especially the HER2-enriched subtype.

Exercise may cut breast cancer risk

16 Oct 2024

Aspirin during pregnancy may enhance cognitive function in children

14 Oct 2024

A prospective cohort study has linked prenatal use of aspirin to better neurocognitive development in offspring.

Aspirin during pregnancy may enhance cognitive function in children

14 Oct 2024

KEYNOTE-522 final data boost pembrolizumab role in early breast cancer

09 Oct 2024 by

Results from the phase III KEYNOTE-522 study presented at ESMO 2024 show a statistically significant and clinically meaningful improvement in overall survival (OS) with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemo alone for previously untreated, high-risk, early-stage triple-negative breast cancer (TNBC).

KEYNOTE-522 final data boost pembrolizumab role in early breast cancer

09 Oct 2024

Women with hypertension face decreased fecundability

09 Oct 2024

Hypertension, regardless of blood pressure control, appears to exert a negative influence on fecundability in women, as reported in a study.

Women with hypertension face decreased fecundability

09 Oct 2024

Excess weight in women, men ups risk of subfertility and pregnancy loss

08 Oct 2024

For both women and men, BMI that is outside of the normal category during the preconception or early-pregnancy periods is a risk factor for lower fecundability, subfertility, and miscarriage, as reported in a cohort study.

Excess weight in women, men ups risk of subfertility and pregnancy loss

08 Oct 2024

Which factors predict pregnancy outcomes in SLE?

07 Oct 2024

In women with systemic lupus erythematosus (SLE), factors such as disease activity prior to and during conception as well as the presence of secondary antiphospholipid syndrome convey heightened risk of adverse pregnancy outcomes, according to the results of a systematic review and meta-analysis.

Which factors predict pregnancy outcomes in SLE?

07 Oct 2024

Breast adiposity in menopause tied to adverse metabolic, body composition parameters

04 Oct 2024

In postmenopausal women, breast adiposity appears to influence various adverse body composition and metabolic factors, suggests a study.

Breast adiposity in menopause tied to adverse metabolic, body composition parameters

04 Oct 2024

Early prediabetes linked to cardiometabolic morbidity during pregnancy

03 Oct 2024

Prediabetes in adolescent or young adult females has been linked to increased likelihood of gestational diabetes and adverse maternal and neonatal outcomes at first birth in a recent retrospective cohort study.

Early prediabetes linked to cardiometabolic morbidity during pregnancy

03 Oct 2024

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Fuzuloparib ± apatinib improves PFS in BRCA-mutated metastatic breast cancer

Fuzuloparib ± apatinib improves PFS in BRCA-mutated metastatic breast cancer

Group intervention may prevent maternal obesity transmission

Group intervention may prevent maternal obesity transmission

Exercise may cut breast cancer risk

Exercise may cut breast cancer risk

Aspirin during pregnancy may enhance cognitive function in children

Aspirin during pregnancy may enhance cognitive function in children

KEYNOTE-522 final data boost pembrolizumab role in early breast cancer

KEYNOTE-522 final data boost pembrolizumab role in early breast cancer

Women with hypertension face decreased fecundability

Women with hypertension face decreased fecundability

Excess weight in women, men ups risk of subfertility and pregnancy loss

Excess weight in women, men ups risk of subfertility and pregnancy loss

Which factors predict pregnancy outcomes in SLE?

Which factors predict pregnancy outcomes in SLE?

Breast adiposity in menopause tied to adverse metabolic, body composition parameters

Breast adiposity in menopause tied to adverse metabolic, body composition parameters

Early prediabetes linked to cardiometabolic morbidity during pregnancy

Early prediabetes linked to cardiometabolic morbidity during pregnancy