News & Updates
Showing Pharmacy articles
Showing
Chemo plus atezolizumab improves survival while preserving life quality in advanced EC
Treatment with carboplatin-paclitaxel (CP) plus atezolizumab results in better quality-adjusted survival in patients with advanced or recurrent endometrial cancer (EC) as compared with CP alone, according to a post hoc analysis of the AtTEnd/ENGOT-EN7 trial.
OCS use improves short-term outcomes in acute preschool wheeze
In a systematic review and individual participant data (IPD) meta-analysis, the use of oral corticosteroids (OCS) improves short-term outcomes in children aged 12–71 months with acute preschool wheeze, more so among children with previous wheeze or asthma and those with moderate-to-severe acute wheeze.
Tadalafil helps recover erectile function in young men with ED
Nearly one in two young men with primary psychogenic erectile dysfunction (ED) treated with tadalafil 5 mg once daily achieve spontaneous medication-free erectile function (EF) at 3 months, as shown in a study. Younger patients tend to have a higher chance of recovery after drug discontinuation.
Navitoclax–ruxolitinib combo doubles spleen response rates in myelofibrosis
In untreated myelofibrosis, using navitoclax in combination with ruxolitinib appears to result in a twofold increase in the number of patients experiencing spleen volume shrinkage, regardless of prognosis, according to updated data from the phase III TRANSFORM-1 trial.
Adjunctive brexpiprazole benefits seen in Asian adults with MDD in real-world
Up to 3 months of treatment with adjunctive brexpiprazole helps with symptom severity in Asian adults with major depressive disorder (MDD) and inadequate response to antidepressants in a real-life clinical setting in Singapore.
Sildenafil shows promise as treatment for Alzheimer’s disease
Sildenafil, a phosphodiesterase type 5 inhibitor, can be a potential treatment for Alzheimer’s disease (AD), as shown in real-world data, AD patient-induced pluripotent stem cells (iPSC)-derived neuron models, and in vivo transgenic mouse model observations, according to a study presented at AAIC 2024.