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GI bleeding a potential complication of direct anticoagulant use in atrial fibrillation

27 Nov 2020

Atrial fibrillation patients receiving direct oral anticoagulants may be at risk of gastrointestinal (GI) bleeding, a recent study has found. This must be taken into consideration when prescribing anticoagulants, particularly to elderly patients.

GI bleeding a potential complication of direct anticoagulant use in atrial fibrillation

27 Nov 2020

Seladelpar improves histologic, biochemical responses in NASH patients

27 Nov 2020 by

Use of the potent and selective PPARδ* agonist seladelpar led to improvements in histologic responses and liver chemistry in patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH), a phase II study has shown.

Seladelpar improves histologic, biochemical responses in NASH patients

27 Nov 2020

Managing hepatitis in primary care

26 Nov 2020

Dr Rajneesh Kumar, a senior consultant at the Department of Gastroenterology and Hepatology, Singapore General Hospital, highlights the high prevalence of hepatitis, and speaks to Roshini Claire Anthony about the transmission, prevention, and treatment of the disease.

Managing hepatitis in primary care

26 Nov 2020

Easy choice for comfortable colonoscopy: Deep over moderate sedation

26 Nov 2020 by

For inflammatory bowel disease patients undergoing ileocolonoscopy, deep sedation with propofol beats moderate sedation with midazolam and fentanyl hands down, owing to less pain, more amnesia, and better experience, a study reports.

Easy choice for comfortable colonoscopy: Deep over moderate sedation

26 Nov 2020

Durable treatment response seen with dapagliflozin-saxagliptin add-on in T2D patients on metformin

25 Nov 2020 by

Reductions in liver fat and adipose tissue volumes were sustained in patients with type 2 diabetes (T2D) with the addition of the SGLT-2* inhibitor dapagliflozin (DAPA) and the DPP-4** inhibitor saxagliptin (SAXA) to metformin (MET), compared with a regimen comprising glimepiride (GLIM)+MET, according to the extension period results of a phase IIIb trial.

Durable treatment response seen with dapagliflozin-saxagliptin add-on in T2D patients on metformin

25 Nov 2020

Fendrix vs Engerix-B: Which vaccine is more effective against HBV in patients with IBD?

24 Nov 2020

Vaccination against hepatitis B virus (HBV) with single-dose Fendrix does not result in a higher response rate compared with double-dose Engerix-B in patients with inflammatory bowel disease (IBD), results of a study have shown, noting that a four-dose schedule is more effective than a three-dose regimen.

Fendrix vs Engerix-B: Which vaccine is more effective against HBV in patients with IBD?

24 Nov 2020

Low liver fat bad for the heart?

23 Nov 2020 by

Distribution of body fat can affect a person’s risk of coronary heart disease (CHD), suggests a study presented at the AASLD 2020 Liver Meeting, which shows that people with high abdominal fat but low liver fat have an increased risk of CHD events than those with other fat distribution.

Low liver fat bad for the heart?

23 Nov 2020

Biologic de-escalation tied to clinical relapse

23 Nov 2020

Dose de-escalation of biologic therapy appears to result in higher rates of clinical relapse, according to results of a systematic review, but the quality of evidence is very low.

Biologic de-escalation tied to clinical relapse

23 Nov 2020

Colon-targeted adsorbent may SHIELD gut microbiome from antibiotic disruption

23 Nov 2020 by

DAV132, a novel, first-in-class, colon-targeted adsorbent capable of adsorbing a wide range of antibiotics, was well-tolerated in hospitalized elderly patients receiving oral/parenteral fluoroquinolones* (FQs), and protected the intestinal microbiota without influencing the plasma concentration of free FQs, the phase II European SHIELD trial has shown.

Colon-targeted adsorbent may SHIELD gut microbiome from antibiotic disruption

23 Nov 2020

CUHK synbiotic formula hastens COVID-19 recovery when added to SoC

23 Nov 2020 by

A synbiotic formula developed by researchers at the Chinese University of Hong Kong (CUHK) is shown to hasten recovery and increase the production of neutralizing antibodies in hospitalized patients with coronavirus disease 2019 (COVID-19).

CUHK synbiotic formula hastens COVID-19 recovery when added to SoC

23 Nov 2020

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GI bleeding a potential complication of direct anticoagulant use in atrial fibrillation

GI bleeding a potential complication of direct anticoagulant use in atrial fibrillation

Seladelpar improves histologic, biochemical responses in NASH patients

Seladelpar improves histologic, biochemical responses in NASH patients

Managing hepatitis in primary care

Managing hepatitis in primary care

Easy choice for comfortable colonoscopy: Deep over moderate sedation

Easy choice for comfortable colonoscopy: Deep over moderate sedation

Durable treatment response seen with dapagliflozin-saxagliptin add-on in T2D patients on metformin

Durable treatment response seen with dapagliflozin-saxagliptin add-on in T2D patients on metformin

Fendrix vs Engerix-B: Which vaccine is more effective against HBV in patients with IBD?

Fendrix vs Engerix-B: Which vaccine is more effective against HBV in patients with IBD?

Low liver fat bad for the heart?

Low liver fat bad for the heart?

Biologic de-escalation tied to clinical relapse

Biologic de-escalation tied to clinical relapse

Colon-targeted adsorbent may SHIELD gut microbiome from antibiotic disruption

Colon-targeted adsorbent may SHIELD gut microbiome from antibiotic disruption

CUHK synbiotic formula hastens COVID-19 recovery when added to SoC

CUHK synbiotic formula hastens COVID-19 recovery when added to SoC